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. 1981 Aug;44(2):166–176. doi: 10.1038/bjc.1981.167

Lymphocytes infiltrating human breast cancers lack K-cell activity and show low levels of NK-cell activity.

O Eremin, R R Coombs, J Ashby
PMCID: PMC2010737  PMID: 6268135

Abstract

Lymphocytes infiltrating human primary mammary carcinomas lack ADCC and show low levels of natural cytotoxicity. The peripheral blood lymphocytes, however, show a variable but prominent level of cytotoxicity. Lymphocyte preparations from breast tumours, when mixed with autologous blood lymphocytes, significantly suppress their prominent killer- (K- and NK-) cell activities.

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Selected References

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