Abstract
From a multiple-regression analysis of prognostic factors and survival in a series of 387 patients with primary breast cancer, a prognostic index has been constructed, based on lymph-node stage, tumour size and pathological grade. This index is more discriminating than lymph-node stage alone, and enables a larger group of patients to be identified with a very poor prognosis.
Full text
PDF





Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Alderson M. R., Hamlin I., Staunton M. D. The relative significance of prognostic factors in breast carcinoma. Br J Cancer. 1971 Dec;25(4):646–656. doi: 10.1038/bjc.1971.80. [DOI] [PMC free article] [PubMed] [Google Scholar]
- BLACK M. M., OPLER S. R., SPEER F. D. Survival in breast cancer cases in relation to the structure of the primary tumor and regional lymph nodes. Surg Gynecol Obstet. 1955 May;100(5):543–551. [PubMed] [Google Scholar]
- BLOOM H. J., RICHARDSON W. W. Histological grading and prognosis in breast cancer; a study of 1409 cases of which 359 have been followed for 15 years. Br J Cancer. 1957 Sep;11(3):359–377. doi: 10.1038/bjc.1957.43. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bishop H. M., Blamey R. W., Elston C. W., Haybittle J. L., Nicholson R. I., Griffiths K. Relationship of oestrogen-receptor status to survival in breast cancer. Lancet. 1979 Aug 11;2(8137):283–284. doi: 10.1016/s0140-6736(79)90295-2. [DOI] [PubMed] [Google Scholar]
- Blamey R. W., Bishop H. M., Blake J. R., Doyle P. J., Elston C. W., Haybittle J. L., Nicholson R. I., Griffiths K. Relationship between primary breast tumor receptor status and patient survival. Cancer. 1980 Dec 15;46(12 Suppl):2765–2769. doi: 10.1002/1097-0142(19801215)46:12+<2765::aid-cncr2820461404>3.0.co;2-c. [DOI] [PubMed] [Google Scholar]
- Blamey R. W., Davies C. J., Elston C. W., Johnson J., Haybittle J. L., Maynard P. V. Prognostic factors in breast cancer -- the formation of a prognostic index. Clin Oncol. 1979 Sep;5(3):227–236. [PubMed] [Google Scholar]
- Freedman L. S., Edwards D. N., McConnell E. M., Downham D. Y. Histological grade and other prognostic factors in relation to survival of patients with breast cancer. Br J Cancer. 1979 Jul;40(1):44–55. doi: 10.1038/bjc.1979.139. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lanzotti V. J., Thomas D. R., Boyle L. E., Smith T. L., Gehan E. A., Samuels M. L. Survival with inoperable lung cancer: an integration of prognostic variables based on simple clinical criteria. Cancer. 1977 Jan;39(1):303–313. doi: 10.1002/1097-0142(197701)39:1<303::aid-cncr2820390147>3.0.co;2-u. [DOI] [PubMed] [Google Scholar]
- Maynard P. V., Davies C. J., Blamey R. W., Elston C. W., Johnson J., Griffiths K. Relationship between oestrogen-receptor content and histological grade in human primary breast tumours. Br J Cancer. 1978 Dec;38(6):745–748. doi: 10.1038/bjc.1978.282. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Myers M. H., Axtell L. M., Zelen M. The use of prognostic factors in predicting survival for breast cancer patients. J Chronic Dis. 1966 Aug;19(8):923–933. doi: 10.1016/0021-9681(66)90008-7. [DOI] [PubMed] [Google Scholar]
- Palmer M. K., Hann I. M., Jones P. M., Evans D. I. A score at diagnosis for predicting length of remission in childhood acute lymphoblastic leukaemia. Br J Cancer. 1980 Dec;42(6):841–849. doi: 10.1038/bjc.1980.331. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wallgren A., Silfverswärd C., Eklund G. Prognostic factors in mammary carcinoma. Acta Radiol Ther Phys Biol. 1976 Feb;15(1):1–16. doi: 10.3109/02841867609132703. [DOI] [PubMed] [Google Scholar]
- Wilkinson G. S., Edgerton F., Wallace H. J., Jr, Reese P., Patterson J., Priore R. Delay, stage of disease and survival from breast cancer. J Chronic Dis. 1979;32(5):365–373. doi: 10.1016/0021-9681(79)90078-x. [DOI] [PubMed] [Google Scholar]