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. 1982 Apr;45(4):543–551. doi: 10.1038/bjc.1982.90

Trends in childhood leukaemia in Britain 1968-1978.

C A Stiller, G J Draper
PMCID: PMC2010975  PMID: 6951601

Abstract

Analysis of recent cancer registrations from Great Britain suggests that there has been an increase in the incidence of childhood acute lymphoid leukaemia for children born after about 1964. The increase is statistically significant for boys aged 0-4 years, and a lesser increase may also have occurred for girls in this age group. Reasons are given for believing that the increase is not purely an artifact attributable to improved registration procedures. Registration data from the Manchester Children's Tumour Registry, Denmark and Sweden support the suggestion that an increase h as occurred. It is not at present possible to say whether a change in incidence will also be seen at higher ages or will be confined to the youngest children, who may represent an aetiologically distinct sub-group. There is no obvious explanation for the findings reported here.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Birch J. M., Swindell R., Marsden H. B., Morris Jones P. H. Childhood leukaemia in North West England 1954-1977: epidemiology, incidence and survival. Br J Cancer. 1981 Mar;43(3):324–329. doi: 10.1038/bjc.1981.51. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Brandt L., Nilsson P. G., Mitelman F. Trends in incidence of acute leukaemia. Lancet. 1979 Nov 17;2(8151):1069–1069. [PubMed] [Google Scholar]
  3. Clemmesen J. Cluster of myeloid leukaemia. Lancet. 1979 Dec 8;2(8154):1238–1239. doi: 10.1016/s0140-6736(79)92353-5. [DOI] [PubMed] [Google Scholar]
  4. Clemmesen J. Statistical studies in the aetiology of malignant neoplasms. 3. Acta Pathol Microbiol Scand Suppl. 1969;209(Suppl):1+–1+. [PubMed] [Google Scholar]
  5. Ericsson J. L., Karnström L., Mattsson B. Childhood cancer in Sweden, 1958-1974. I. Incidence and mortality. Acta Paediatr Scand. 1978 Jul;67(4):425–432. doi: 10.1111/j.1651-2227.1978.tb16349.x. [DOI] [PubMed] [Google Scholar]
  6. Freedman L., Dent N. A., Hunt C., Payne P. M., Smith P. G. Letter: Incidence of childhood leukaemia. Lancet. 1974 May 25;1(7865):1059–1059. doi: 10.1016/s0140-6736(74)90466-8. [DOI] [PubMed] [Google Scholar]
  7. HEWITT D. Some features of leukaemia mortality. Br J Prev Soc Med. 1955 Apr;9(2):81–88. doi: 10.1136/jech.9.2.81. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Kemp I. W., Stein G. J., Heasman M. A. Myeloid leukaemia in Scotland. Lancet. 1980 Oct 4;2(8197):732–734. doi: 10.1016/s0140-6736(80)91948-0. [DOI] [PubMed] [Google Scholar]
  9. Leck I., Benn R. T., Smith A. Changes in myeloid leukaemia incidence? Lancet. 1980 Oct 4;2(8197):749–750. doi: 10.1016/s0140-6736(80)91973-x. [DOI] [PubMed] [Google Scholar]
  10. Stewart A. Aetiology of Childhood Malignancies. Br Med J. 1961 Feb 18;1(5224):452–460. doi: 10.1136/bmj.1.5224.452. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Waterhouse J. A., Powell J. Letter: Incidence of childhood leukaemia. Lancet. 1973 Dec 1;2(7840):1274–1274. doi: 10.1016/s0140-6736(73)91025-8. [DOI] [PubMed] [Google Scholar]

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