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. 1982 Jun;45(6):851–859. doi: 10.1038/bjc.1982.137

Five years' experience with ChlVPP: effective low-toxicity combination chemotherapy for Hodgkin's disease.

P J Dady, T J McElwain, D E Austin, A Barrett, M J Peckham
PMCID: PMC2011032  PMID: 7093120

Abstract

Since 1975, 191 patients with Hodgkin's disease have been treated with a combination of chlorambucil, vinblastine, procarbazine and prednisolone (ChlVPP). Complete remission rates were 73% for previously untreated patients, 91% for patients previously treated with radiotherapy and 55% for patients previously treated with chemotherapy. In 59 patients with advanced disease who received no other treatment, a 5-year survival rate of 66% was comparable with that achieved by more toxic mustine-containing combinations. ChlVPP has few side effects, is easily given to outpatients, and can be combined with elective radiotherapy in selected patients.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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