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. 1982 Jul;46(1):18–21. doi: 10.1038/bjc.1982.159

The site of binding of anti-CEA antibodies to tumour CEA in vivo: an immunocytochemical and autoradiographic approach.

V Moshakis, M G Ormerod, J H Westwood, S Imrie, A M Neville
PMCID: PMC2011056  PMID: 7104194

Abstract

Radiolabelled affinity-purified antibody to carcinoembryonic antigen (CEA) was injected i.v. into immune-suppressed mice carrying xenografts of human breast carcinoma. Its distribution in the tumours was examined by a combination of immunocytochemistry and autoradiography. The antibody interacted predominantly with the CEA in the extracellular tumour space, rather than on the cell membrane or cytoplasm.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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