Skip to main content
NCBI home page
British Journal of Cancer logoLink to British Journal of Cancer
. 1982 Sep;46(3):440–443. doi: 10.1038/bjc.1982.222

Metabolism of 5-methyltetrahydrofolate by rats bearing the Walker 256 carcinosarcoma.

J C Kennelly, J A Blair, A E Pheasant
PMCID: PMC2011108  PMID: 7126430

Full text

PDF
440

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ashe H., Clark B. R., Chu F., Hardy D. N., Halpern B. C., Halpern R. M., Smith R. A. N5-methyltetrahydrofolate: homocysteine methyltransferase activity in extracts from normal, malignant and embryonic tissue culture cells. Biochem Biophys Res Commun. 1974 Mar 25;57(2):417–425. doi: 10.1016/0006-291x(74)90947-4. [DOI] [PubMed] [Google Scholar]
  2. Barford P. A., Staff F. J., Blair J. A. The metabolic fate of (2-14C)folic acid and a mixture of (2-14C)- and (3',5',9-3h)-folic acid in the rat. Biochem J. 1978 Aug 15;174(2):579–583. doi: 10.1042/bj1740579. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Barford P. A., Staff R. J., Blair J. A. Retained folates in the rat. Biochem J. 1977 Jun 15;164(3):601–605. doi: 10.1042/bj1640601. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Connor M. J., Pheasant A. E., Blair J. A. The identification of p-acetamidobenzoate as a folate degradation product in rat urine. Biochem J. 1979 Mar 15;178(3):795–797. doi: 10.1042/bj1780795. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Gready J. E. Dihydrofolate reductase: the current story. Nature. 1979 Dec 13;282(5740):674–675. doi: 10.1038/282674a0. [DOI] [PubMed] [Google Scholar]
  6. Halpern B. C., Clark B. R., Hardy D. N., Halpern R. M., Smith R. A. The effect of replacement of methionine by homocystine on survival of malignant and normal adult mammalian cells in culture. Proc Natl Acad Sci U S A. 1974 Apr;71(4):1133–1136. doi: 10.1073/pnas.71.4.1133. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Hoffman R. M., Erbe R. W. High in vivo rates of methionine biosynthesis in transformed human and malignant rat cells auxotrophic for methionine. Proc Natl Acad Sci U S A. 1976 May;73(5):1523–1527. doi: 10.1073/pnas.73.5.1523. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Kennelly J. C., Blair J. A., Pheasant A. E. The metabolism of 5-methyltetrahydrofolic acid in the rat [proceedings]. Biochem Soc Trans. 1979 Aug;7(4):648–649. doi: 10.1042/bst0070648. [DOI] [PubMed] [Google Scholar]
  9. Kreis W., Goodenow M. Methionine requirement and replacement by homocysteine in tissue cultures of selected rodent and human malignant and normal cells. Cancer Res. 1978 Aug;38(8):2259–2262. [PubMed] [Google Scholar]
  10. Mangum J. H., Murray B. K., North J. A. Vitamin B 12 dependent methionine biosynthesis in cultured mammalian cells. Biochemistry. 1969 Sep;8(9):3496–3499. doi: 10.1021/bi00837a002. [DOI] [PubMed] [Google Scholar]
  11. Saleh A. M., Pheasant A. E., Blair J. A. Folate catabolism in tumour-bearing rats and rats treated with methotrexate. Br J Cancer. 1981 Nov;44(5):700–708. doi: 10.1038/bjc.1981.256. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from British Journal of Cancer are provided here courtesy of Cancer Research UK

RESOURCES