Abstract
Bronchoalveolar lavage (BAL) was performed in 47 patients (24 smokers, 18 ex-smokers and 5 who never smoked). Cytocentrifuged preparations were stained with May-Grunwald-Giemsa (MGG) and differential counts of pulmonary alveolar macrophages (PAM) with smokers' inclusions were performed. The data supported an exponential reduction in this percentage and indicated that about 3 years elapsed before this percentage approximated to the values in patients who had never smoked. Electron microscopy was performed on eight BALs and the results supported those obtained by light microscopy.
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- Cole P., Turton C., Lanyon H., Collins J. Bronchoalveolar lavage for the preparation of free lung cells: technique and complications. Br J Dis Chest. 1980 Jul;74(3):273–278. doi: 10.1016/0007-0971(80)90055-8. [DOI] [PubMed] [Google Scholar]
- Martin R. R. Altered morphology and increased acid hydrolase content of pulmonary macrophages from cigarette smokers. Am Rev Respir Dis. 1973 Apr;107(4):596–601. doi: 10.1164/arrd.1973.107.4.596. [DOI] [PubMed] [Google Scholar]
- Pratt S. A., Finley T. N., Smith M. H., Ladman A. J. A comparison of alveolar macrophages and pulmonary surfactant(?) obtained from the lungs of human smokers and nonsmokers by endobronchial lavage. Anat Rec. 1969 Apr;163(4):497–507. doi: 10.1002/ar.1091630402. [DOI] [PubMed] [Google Scholar]
- Warr G. A., Martin R. R. Histochemical staining and in vitro spreading of human pulmonary alveolar macrophages: variability with cigarette smoking status. J Reticuloendothel Soc. 1978 Jan;23(1):53–62. [PubMed] [Google Scholar]