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British Journal of Experimental Pathology logoLink to British Journal of Experimental Pathology
. 1986 Aug;67(4):563–569.

Presence of I-region gene products on the cells and their products of the dengue virus-induced suppressor pathway.

M I Shukla, U C Chaturvedi
PMCID: PMC2013043  PMID: 2427101

Abstract

We have studied both the cells and the suppressor factors of the dengue virus-induced suppressor pathway for the presence of I-region gene products. The suppressor activity of Ts1, Ts2 and Ts3 cells was abrogated by treatment with anti I-Jk or I-Ak anti-sera and complement. Both the suppressor factors were absorbed out by anti I-Jk and I-Ak immunosorbent columns. The activity of the suppressor factor was abolished by treatment with anti I-Jk antisera. Macrophage presentation of suppressor factor to precursors of Ts2 cells was abolished by treatment with anti I-Ak antisera and complement but not by anti I-Jk antisera. Thus I-region gene products were found throughout the dengue virus induced suppressor pathway.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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