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British Journal of Experimental Pathology logoLink to British Journal of Experimental Pathology
. 1986 Feb;67(1):141–147.

Different effects of the polysaccharide levan on the oncogenicity of cells of two variants of Lewis lung carcinoma.

Y Stark, J Leibovici
PMCID: PMC2013074  PMID: 3947532

Abstract

A marked difference in sensitivity to the direct effect of the polysaccharide levan on tumour cells was observed between two variants of malignancy of Lewis lung carcinoma: cells of the more malignant variant (3LL-M) were much more sensitive to the drug than those of the less malignant tumour (3LL). A gradual decrease in tumorigenicity following preincubation with increasing levan concentrations was observed with both variants, but statistically significant inhibition was observed at lower levan concentrations with 3LL-M than with 3LL.

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Selected References

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