Abstract
Macrophages and mast cells in masseter muscle from normal and dystrophic mice were studied by light and electron microscopy. Acid phosphatase activity and FITC-dextran were used to identify and describe macrophages. Toluidine blue was used as a marker for mast cells. In dystrophic muscle, the number of macrophages was greatly increased and they contained large amounts of phagocytozed material. In normal muscle, mast cells were rarely identified whereas dystrophic muscle contained many mast cells which were often in close contact with macrophages.
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- Altman F. P. The use of industrial chemicals for research purposes. Histochem J. 1977 Mar;9(2):247–248. doi: 10.1007/BF01003635. [DOI] [PubMed] [Google Scholar]
- Christie K. N., Modi B. V. Some histochemical observations on invasive cells in a myopathy induced in rats with 5-hydroxytryptamine. Neuropathol Appl Neurobiol. 1984 Nov-Dec;10(6):447–460. doi: 10.1111/j.1365-2990.1984.tb00393.x. [DOI] [PubMed] [Google Scholar]
- Gopalan P., Dufresne M. J., Warner A. H. Evidence for a defective thiol protease inhibitor in skeletal muscle of mice with hereditary muscular dystrophy. Biochem Cell Biol. 1986 Oct;64(10):1010–1019. doi: 10.1139/o86-134. [DOI] [PubMed] [Google Scholar]
- Mikkelsen H., Kirkeby S. Electron microscopic and histochemical studies on dystrophic masseter muscle. Scand J Dent Res. 1985 Dec;93(6):529–538. doi: 10.1111/j.1600-0722.1985.tb01351.x. [DOI] [PubMed] [Google Scholar]
- Schnyder J., Baggiolini M. Secretion of lysosomal hydrolases by stimulated and nonstimulated macrophages. J Exp Med. 1978 Aug 1;148(2):435–450. doi: 10.1084/jem.148.2.435. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Steinman R. M., Mellman I. S., Muller W. A., Cohn Z. A. Endocytosis and the recycling of plasma membrane. J Cell Biol. 1983 Jan;96(1):1–27. doi: 10.1083/jcb.96.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tanner A. R., Arthur M. J., Wright R. Macrophage activation, chronic inflammation and gastrointestinal disease. Gut. 1984 Jul;25(7):760–783. doi: 10.1136/gut.25.7.760. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Walter R. J., Berlin R. D., Pfeiffer J. R., Oliver J. M. Polarization of endocytosis and receptor topography on cultured macrophages. J Cell Biol. 1980 Jul;86(1):199–211. doi: 10.1083/jcb.86.1.199. [DOI] [PMC free article] [PubMed] [Google Scholar]