Skip to main content
PMC home page
The American Journal of Pathology logoLink to The American Journal of Pathology
. 1968 May;52(5):983–1011.

Pancreatic acinar cell regeneration.

P J Fitzgerald, L Herman, B Carol, A Roque, W H Marsh, L Rosenstock, C Richards, D Perl
PMCID: PMC2013346  PMID: 5646513

Full text

PDF
983

Images in this article

1001Fig. 1
on p.1001
1003Fig. 2
on p.1003
1005Fig. 3
on p.1005
1007Fig. 4
on p.1007
1009Fig. 5
on p.1009
1011Fig. 6
on p.1011

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BUCHER N. L. REGENERATION OF MAMMALIAN LIVER. Int Rev Cytol. 1963;15:245–300. doi: 10.1016/s0074-7696(08)61119-5. [DOI] [PubMed] [Google Scholar]
  2. CARO L. G. Electron microscopic radioautography of thin sections: the Golgi zone as a site of protein concentration in pancreatic acinar cells. J Biophys Biochem Cytol. 1961 May;10:37–45. doi: 10.1083/jcb.10.1.37. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. CASTRINI G. Comportamento degli acidi nucleinici nel pancreas esocrino di ratti trattati con etionina. Riv Biol. 1954 Jul-Sep;46(3):413–430. [PubMed] [Google Scholar]
  4. CRANE W. A., DUTTA L. P. THE INFLUENCE OF AGE AND HORMONAL STATUS ON THE UPTAKE OF TRITIATED THYMIDINE BY RAT PANCREAS. J Endocrinol. 1964 Feb;28:341–342. doi: 10.1677/joe.0.0280341. [DOI] [PubMed] [Google Scholar]
  5. DALY M. M., MIRSKY A. E. Formation of protein in the pancreas. J Gen Physiol. 1952 Nov;36(2):243–254. doi: 10.1085/jgp.36.2.243. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. De Duve C., Wattiaux R. Functions of lysosomes. Annu Rev Physiol. 1966;28:435–492. doi: 10.1146/annurev.ph.28.030166.002251. [DOI] [PubMed] [Google Scholar]
  7. FITZGERALD P. J., ALVIZOURI M. Rapid restitution of the rat pancreas following acinar cell necrosis subsequent to ethionine. Nature. 1952 Nov 29;170(4335):929–930. doi: 10.1038/170929b0. [DOI] [PubMed] [Google Scholar]
  8. FITZGERALD P. J., HERMAN L. DEGENERATION AND REGENERATION OF THE PANCREAS. Bull N Y Acad Med. 1965 Jul;41:804–810. [PMC free article] [PubMed] [Google Scholar]
  9. FITZGERALD P. J. The problem of the precursor cell of regenerating pancreatic acinar epithelium. Lab Invest. 1960 Jan-Feb;9:67–85. [PubMed] [Google Scholar]
  10. Fitzgerald P. J., Carol B. M., Rosenstock L. Pancreatic acinar cell regeneration. Nature. 1966 Nov 5;212(5062):594–596. doi: 10.1038/212594a0. [DOI] [PubMed] [Google Scholar]
  11. Fitzgerald P. J., Vinijchaikul K., Carol B., Rosenstock L. Pancreatic acinar cell regeneration. 3. DNA synthesis of pancreas nuclei as indicated by thymidine-H3 autoradiography. Am J Pathol. 1968 May;52(5):1039–1065. [PMC free article] [PubMed] [Google Scholar]
  12. HERMAN L., FITZGERALD P. J. Restitution of pancreatic acinar cells following ethionine. J Cell Biol. 1962 Feb;12:297–312. doi: 10.1083/jcb.12.2.297. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. HERMAN L., FITZGERALD P. J. The degenerative changes in pancreatic acinar cells caused by DL-ethionine. J Cell Biol. 1962 Feb;12:277–296. doi: 10.1083/jcb.12.2.277. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. HERMAN L., FITZGERALD P. J. The fine structure of the Golgi body following thyroid stimulation and pancreatic regeneration. Trans N Y Acad Sci. 1961 Feb;23:332–345. doi: 10.1111/j.2164-0947.1961.tb01360.x. [DOI] [PubMed] [Google Scholar]
  15. JACOB F., MONOD J. Genetic regulatory mechanisms in the synthesis of proteins. J Mol Biol. 1961 Jun;3:318–356. doi: 10.1016/s0022-2836(61)80072-7. [DOI] [PubMed] [Google Scholar]
  16. Jamieson J. D., Palade G. E. Intracellular transport of secretory proteins in the pancreatic exocrine cell. I. Role of the peripheral elements of the Golgi complex. J Cell Biol. 1967 Aug;34(2):577–596. doi: 10.1083/jcb.34.2.577. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Jamieson J. D., Palade G. E. Intracellular transport of secretory proteins in the pancreatic exocrine cell. II. Transport to condensing vacuoles and zymogen granules. J Cell Biol. 1967 Aug;34(2):597–615. doi: 10.1083/jcb.34.2.597. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Johnson H. A., Vera Roman J. M. Compensatory renal enlargement. Hypertrophy versus hyperplasia. Am J Pathol. 1966 Jul;49(1):1–13. [PMC free article] [PubMed] [Google Scholar]
  19. KINNEY T. D., KAUFMAN N., KLAVINS J. V. Regeneration of pancreatic acini during ethionine administration. AMA Arch Pathol. 1955 Dec;60(6):639–643. [PubMed] [Google Scholar]
  20. LEBLOND C. P., WALKER B. E. Renewal of cell populations. Physiol Rev. 1956 Apr;36(2):255–276. doi: 10.1152/physrev.1956.36.2.255. [DOI] [PubMed] [Google Scholar]
  21. LIOSNER L. D. ACADEMY OF MEDICAL SCIENCES OF THE U.S.S.R., MOSCOW INSTITUTE OF EXPERIMENTAL BIOLOGY. RESEARCH REPORT 1961-1963 OF THE LABORATORY FOR GROWTH AND DEVELOPMENT. Folia Biol (Praha) 1964;10:472–479. [PubMed] [Google Scholar]
  22. LUFT J. H. Improvements in epoxy resin embedding methods. J Biophys Biochem Cytol. 1961 Feb;9:409–414. doi: 10.1083/jcb.9.2.409. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Marsh W. H., Goldsmith S., Crocco J., Fitzgerald P. J. Pancreatic acinar cell regeneration. II. Enzymatic, nucleic acid, and protein changes. Am J Pathol. 1968 May;52(5):1013–1037. [PMC free article] [PubMed] [Google Scholar]
  24. NOVIKOFF A. B., BEAUFAY H., DE DUVE C. Electron microscopy of lysosomerich fractions from rat liver. J Biophys Biochem Cytol. 1956 Jul 25;2(4 Suppl):179–184. [PMC free article] [PubMed] [Google Scholar]
  25. OLIVER J. Correlations of structure and function and mechanisms of recovery in acute tubular necrosis. Am J Med. 1953 Oct;15(4):535–557. doi: 10.1016/0002-9343(53)90143-0. [DOI] [PubMed] [Google Scholar]
  26. PALADE G. E., SIEKEVITZ P. Pancreatic microsomes; an integrated morphological and biochemical study. J Biophys Biochem Cytol. 1956 Nov 25;2(6):671–690. doi: 10.1083/jcb.2.6.671. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. PARADISI F., CAVAZZUTI F. EXOCRINE PANCREAS AND EXPERIMENTAL DIETARY LESIONS. Gastroenterologia. 1965;103:1–14. doi: 10.1159/000202172. [DOI] [PubMed] [Google Scholar]
  28. Penman S., Smith I., Holtzman E. Ribosomal RNA synthesis and processing in a particulate site in the HeLa cell nucleus. Science. 1966 Nov 11;154(3750):786–789. doi: 10.1126/science.154.3750.786. [DOI] [PubMed] [Google Scholar]
  29. REYNOLDS E. S. The use of lead citrate at high pH as an electron-opaque stain in electron microscopy. J Cell Biol. 1963 Apr;17:208–212. doi: 10.1083/jcb.17.1.208. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. RICHARDS C., FITZGERALD P. J., CAROL B., ROSENSTOCK L., LIPKIN L. SEGMENTAL DIVISION OF THE RAT PANCREAS FOR EXPERIMENTAL PROCEDURES. Lab Invest. 1964 Oct;13:1303–1321. [PubMed] [Google Scholar]
  31. ROQUE A. L., JAFAREY N. A., COULTER P. A STAIN FOR THE HISTOCHEMICAL DEMONSTRATION OF NUCLEIC ACIDS. Exp Mol Pathol. 1965 Jun;11:266–274. doi: 10.1016/0014-4800(65)90002-x. [DOI] [PubMed] [Google Scholar]
  32. SABATINI D. D., BENSCH K., BARRNETT R. J. Cytochemistry and electron microscopy. The preservation of cellular ultrastructure and enzymatic activity by aldehyde fixation. J Cell Biol. 1963 Apr;17:19–58. doi: 10.1083/jcb.17.1.19. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. SINGER M., INOUE S. THE NERVE AND THE EPIDERMAL APICAL CAP IN REGENERATION OF THE FORELIMB OF ADULT TRITURUS. J Exp Zool. 1964 Feb;155:105–116. doi: 10.1002/jez.1401550108. [DOI] [PubMed] [Google Scholar]
  34. STEMPAK J. G., WARD R. T. AN IMPROVED STAINING METHOD FOR ELECTRON MICROSCOPY. J Cell Biol. 1964 Sep;22:697–701. doi: 10.1083/jcb.22.3.697. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. TSUKADA K., LIEBERMAN I. METABOLISM OF NUCLEOLAR RIBONUCLEIC ACID AFTER PARTIAL HEPATECTOMY. J Biol Chem. 1964 May;239:1564–1568. [PubMed] [Google Scholar]
  36. Tisher C. C., Bulger R. E., Trump B. F. Human renal ultrastructure. I. Proximal tubule of healthy individuals. Lab Invest. 1966 Aug;15(8):1357–1394. [PubMed] [Google Scholar]
  37. WACHSTEIN M., MEISEL E. Cellular changes accompanying the degenerative and regenerative phase of ethionine-induced pancreatic damage in the rat. Lab Invest. 1953 Jul-Aug;2(4):253–265. [PubMed] [Google Scholar]
  38. WATSON M. L. Staining of tissue sections for electron microscopy with heavy metals. J Biophys Biochem Cytol. 1958 Jul 25;4(4):475–478. doi: 10.1083/jcb.4.4.475. [DOI] [PMC free article] [PubMed] [Google Scholar]
  39. WEISBLUM B., HERMAN L., FITZGERALD P. J. Changes in pancreatic acinar cells during protein deprivation. J Cell Biol. 1962 Feb;12:313–327. doi: 10.1083/jcb.12.2.313. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from The American Journal of Pathology are provided here courtesy of American Society for Investigative Pathology

RESOURCES