Skip to main content
NCBI home page
The American Journal of Pathology logoLink to The American Journal of Pathology
. 1969 Dec;57(3):489–521.

Pancreas acinar cell differentiation. II. Comparative DNA and protein synthesis of the embryonic rat pancreas and the pancreatic anlage grown in organ culture.

I Parsa, W H Marsh, P J Fitzgerald
PMCID: PMC2013633  PMID: 5361383

Full text

PDF
489

Images in this article

511Fig 1
on p.511
515Fig 3
on p.515
513Fig 2
on p.513
517Fig 4
on p.517
519Fig 5
on p.519
521Fig 6
on p.521

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ALLFREY V. G., FAULKNER R., MIRSKY A. E. ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS. Proc Natl Acad Sci U S A. 1964 May;51:786–794. doi: 10.1073/pnas.51.5.786. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Carol B., Fitzgerald P. J. Pancreatic acinar cell regeneration. VI. Estimation of error of the autoradiographic labeling index (thymidine-H3)--maximum possible error (MPRE) and sensitivity (S). Am J Pathol. 1968 Dec;53(6):971–987. [PMC free article] [PubMed] [Google Scholar]
  3. FITZGERALD P. J., EIDINOFF M. L., KNOLL J. E., SIMMEL E. B. Tritium in radioautography. Science. 1951 Nov 9;114(2967):494–498. doi: 10.1126/science.114.2967.494. [DOI] [PubMed] [Google Scholar]
  4. FITZGERALD P. J., SIMMEL E., WEINSTEIN J., MARTIN C. Radioautography; theory, technic, and applications. Lab Invest. 1953 May-Jun;2(3):181–222. [PubMed] [Google Scholar]
  5. Fitzgerald P. J., Carol B. M., Rosenstock L. Pancreatic acinar cell regeneration. Nature. 1966 Nov 5;212(5062):594–596. doi: 10.1038/212594a0. [DOI] [PubMed] [Google Scholar]
  6. Fitzgerald P. J., Carol B., Lipkin L., Rosenstock L. Pancreatic acinar cell regeneration. V. Analysis of variance of the autoradiographic labeling index (thymidine-H3). Am J Pathol. 1968 Dec;53(6):953–970. [PMC free article] [PubMed] [Google Scholar]
  7. Fitzgerald P. J., Vinijchaikul K., Carol B., Rosenstock L. Pancreatic acinar cell regeneration. 3. DNA synthesis of pancreas nuclei as indicated by thymidine-H3 autoradiography. Am J Pathol. 1968 May;52(5):1039–1065. [PMC free article] [PubMed] [Google Scholar]
  8. GENTRY G. A., MORSE P. A., Jr, IVES D. H., GEBERT R., POTTER V. R. PYRIMIDINE METABOLISM IN TISSUE CULTURE CELLS DERIVED FROM RAT HEPATOMAS. II. THYMIDINE UPTAKE IN SUSPENSION CULTURES DERIVED FROM THE NOVIKOFF HEPATOMA. Cancer Res. 1965 May;25:509–516. [PubMed] [Google Scholar]
  9. GOLDSTEIN L. Localization of nucleusspecific protein as shown by transplantation experiments in Amoeba proteus. Exp Cell Res. 1958 Dec;15(3):635–637. doi: 10.1016/0014-4827(58)90118-6. [DOI] [PubMed] [Google Scholar]
  10. GOLOSOW N., GROBSTEIN C. Epitheliomesenchymal interaction in pancreatic morphogenesis. Dev Biol. 1962 Apr;4:242–255. doi: 10.1016/0012-1606(62)90042-8. [DOI] [PubMed] [Google Scholar]
  11. GROBSTEIN C. CYTODIFFERENTIATION AND ITS CONTROLS. Science. 1964 Feb 14;143(3607):643–650. doi: 10.1126/science.143.3607.643. [DOI] [PubMed] [Google Scholar]
  12. HUANG R. C., BONNER J. Histone, a suppressor of chromosomal RNA synthesis. Proc Natl Acad Sci U S A. 1962 Jul 15;48:1216–1222. doi: 10.1073/pnas.48.7.1216. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Lehv M., Fitzgerald P. J. Pancreatic acinar cell regeneration. IV. Regeneration after resection. Am J Pathol. 1968 Oct;53(4):513–535. [PMC free article] [PubMed] [Google Scholar]
  14. Murrell L. R. Mammalian pancreatic islet tissue in organ culture. I. Methods of culture and in vitro histogenesis. Exp Cell Res. 1966 Feb;41(2):350–364. doi: 10.1016/s0014-4827(66)80143-x. [DOI] [PubMed] [Google Scholar]
  15. Murrell L. R., Morgan C. R., Lazarow A. Mammalian pancreatic islet tissue in organ culture. II. Insulin contents of tissues and culture medium. Exp Cell Res. 1966 Feb;41(2):365–375. doi: 10.1016/s0014-4827(66)80144-1. [DOI] [PubMed] [Google Scholar]
  16. Ord M. G., Stocken L. A. Further studies on phosphorylation and the thiol-disulphide ratio of histones in growth and development. Biochem J. 1969 Mar;112(1):81–89. doi: 10.1042/bj1120081. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Parsa I., Marsh W. H., Fitzgerald P. J. Pancreas acinar cell differentiation. I. Morphologic and enzymatic comparisons of embryonic rat pancreas anlage grown in organ culture. Am J Pathol. 1969 Dec;57(3):457–487. [PMC free article] [PubMed] [Google Scholar]
  18. Przybylski R. J. Cytodifferentiation of the chick pancreas. 3. The content and synthesis of ribonucleic acid and proteins in developing acinar cells. J Morphol. 1967 Oct;123(2):173–190. doi: 10.1002/jmor.1051230206. [DOI] [PubMed] [Google Scholar]
  19. RICHARDS C., FITZGERALD P. J., CAROL B., ROSENSTOCK L., LIPKIN L. SEGMENTAL DIVISION OF THE RAT PANCREAS FOR EXPERIMENTAL PROCEDURES. Lab Invest. 1964 Oct;13:1303–1321. [PubMed] [Google Scholar]
  20. ROQUE A. L., JAFAREY N. A., COULTER P. A STAIN FOR THE HISTOCHEMICAL DEMONSTRATION OF NUCLEIC ACIDS. Exp Mol Pathol. 1965 Jun;11:266–274. doi: 10.1016/0014-4800(65)90002-x. [DOI] [PubMed] [Google Scholar]
  21. WARSHAWSKY H., LEBLOND C. P., DROZ B. Synthesis and migration of proteins in the cells of the exocrine pancreas as revealed by specific activity determination from radioautographs. J Cell Biol. 1963 Jan;16:1–24. doi: 10.1083/jcb.16.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. WESSELLS N. K. ACQUISITION OF ACTINOMYCIN D INSENSITIVITY DURING DIFFERENTIATION OF PANCREAS EXOCRINE CELLS. Dev Biol. 1964 Feb;9:92–114. doi: 10.1016/0012-1606(64)90016-8. [DOI] [PubMed] [Google Scholar]
  23. WESSELLS N. K. DNA SYNTHESIS, MITOSIS, AND DIFFERENTIATION IN PANCREATIC ACINAR CELLS IN VITRO. J Cell Biol. 1964 Mar;20:415–433. doi: 10.1083/jcb.20.3.415. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Wells L. J., Erlandsen S. L., Eguchi Y. Development of pancreases and adrenals of rat embryos in organ culture. Anat Rec. 1968 Feb;160(2):201–205. doi: 10.1002/ar.1091600206. [DOI] [PubMed] [Google Scholar]
  25. ZAGURY D. [The culture of the rat endocrine pancreas and insulogenesis]. C R Hebd Seances Acad Sci. 1959 Dec 21;249:2834–2835. [PubMed] [Google Scholar]

Articles from The American Journal of Pathology are provided here courtesy of American Society for Investigative Pathology

RESOURCES