Abstract
Congenital anomalies caused 3.43 perinatal deaths/1000 births, as reported in a large prospective study. At all gestational ages the mortality rates progressively increased when gravidas smoked more than 10 cigarettes/day. An excessive death rate was also found in males, in offspring of mothers over 39 years of age, and in women of low socioeconomic status. Placentas associated with the malformed infants had an increased frequency of single umbilical arteries and abnormal insertions of fetal membranes and umbilical cords into the placenta.
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Selected References
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- Alberman E. D., Goldstein H. Possible teratogenic effect of cigarette smoking. Nature. 1971 Jun 25;231(5304):529–530. doi: 10.1038/231529a0. [DOI] [PubMed] [Google Scholar]
- Andrews J., McGarry J. M. A community study of smoking in pregnancy. J Obstet Gynaecol Br Commonw. 1972 Dec;79(12):1057–1073. doi: 10.1111/j.1471-0528.1972.tb11887.x. [DOI] [PubMed] [Google Scholar]
- Comstock G. W., Shah F. K., Meyer M. B., Abbey H. Low birth weight and neonatal mortality rate related to maternal smoking and socioeconomic status. Am J Obstet Gynecol. 1971 Sep;111(1):53–59. doi: 10.1016/0002-9378(71)90926-4. [DOI] [PubMed] [Google Scholar]
- HERTIG A. T., ROCK J., ADAMS E. C. A description of 34 human ova within the first 17 days of development. Am J Anat. 1956 May;98(3):435–493. doi: 10.1002/aja.1000980306. [DOI] [PubMed] [Google Scholar]
- LOWE C. R. Effect of mothers' smoking habits on birth weight of their children. Br Med J. 1959 Oct 10;2(5153):673–676. doi: 10.1136/bmj.2.5153.673. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mau G., Netter P. Die Auswirkungen des väterlichen Zigarettenkonsums auf die perinatale Sterblichkeit und die Missbildungshäufigkeit. Dtsch Med Wochenschr. 1974 May 24;99(21):1113–1118. doi: 10.1055/s-0028-1107900. [DOI] [PubMed] [Google Scholar]
- Myrianthopoulos N. C., French K. S. An application of the U.S. Bureau of the Census socioeconomic index to a large, diversified patient population. Soc Sci Med. 1968 Sep;2(3):283–299. doi: 10.1016/0037-7856(68)90004-8. [DOI] [PubMed] [Google Scholar]
- Naeye R. L. Causes of perinatal mortality in the US Collaborative Perinatal Project. JAMA. 1977 Jul 18;238(3):228–229. [PubMed] [Google Scholar]
- Roberts C. J., Powell R. G. Interrelation of the common congenital malformations: some aetiological implications. Lancet. 1975 Nov 1;2(7940):848–850. doi: 10.1016/s0140-6736(75)90237-8. [DOI] [PubMed] [Google Scholar]
- WORCESTER J., STEVENSON S. S., RICE R. G. 677 congenitally malformed infants and associated gestational characteristics. II. Parental factors. Pediatrics. 1950 Aug;6(2):208–222. [PubMed] [Google Scholar]