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. 1978 Oct;93(1):103–116.

Morphologic abnormalities in potassium-deficient dogs.

C L Tate, W J Bagdon, D L Bokelman
PMCID: PMC2018329  PMID: 696799

Abstract

Potassium deficiency was produced in 16 dogs by means of a diet containing less than 0.03% potassium. Decreases in serum potassium were first observed after 3 weeks. Morphologic changes occurred only in heart, skeletal muscle, and kidney. Focal myocardial necrosis was observed in 6 of 16 deficient dogs, and skeletal muscle degeneration and necrosis were observed in 14 of 16 deficient dogs. A complex nephropathy consisting primarily of epithelial hypertrophy and hyperplasia in the collecting tubules of the inner stripe of the outer medulla occurred in all the deficient dogs.

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Selected References

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