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. 2001 Jun;47:1179–1181.

Congenital cytomegalovirus infection. Is there a breakthrough?

B Bar-Oz 1, M Berkovitch 1, L Ford-Jones 1, G Koren 1
PMCID: PMC2018521  PMID: 11421042

Abstract

QUESTION: My 26-year-old patient is planning her first pregnancy in the coming month. She works in a day-care centre. Recently, two cases of cytomegalovirus (CMV) infection were diagnosed in her class. What tests should she have before and during the pregnancy, and how should I care for her? ANSWER: Cytomegalovirus infection, the most common congenital viral infection in humans, carries high risk of long-term morbidity and mortality. Seronegative mothers of children in day-care centres are at as high risk of acquiring the infection as day-care workers themselves. The immune status of at-risk patients should be evaluated as pregnancy progresses. Evidence of fetal infection does not necessarily mean fetal disease or damage. With a primary-infected fetus, termination of pregnancy might be discussed with the parents.

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Selected References

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