Figure 3.

Area-proportional Venn diagram of cross recognition. The expressed whole genome of HIV-1 clade B or clade C were digested as 413 overlapping peptides and the two sets of peptides were tested in ELISPOT assay for each subject enrolled in this study. Cross-recognition of CTL responses to clade B and Clade C peptides were assessed by the classification of (i) both B and C peptides not recognized, (ii) both B and C peptides recognized by at least one subject, (iii) only C peptides recognized by at least one subject and (iv) only B peptides recognized by at least one subject.