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. 1994 Oct;60(10):3881–3883. doi: 10.1128/aem.60.10.3881-3883.1994

Identification of a heroin esterase in Rhodococcus sp. strain H1.

G W Cameron 1, K N Jordan 1, P J Holt 1, P B Baker 1, C R Lowe 1, N C Bruce 1
PMCID: PMC201902  PMID: 7986057

Abstract

A strain of a Rhodococcus sp. (termed H1) capable of utilizing heroin as its sole carbon and energy source was isolated by selective enrichment. An inducible heroin esterase was partially purified and shown to catalyze the hydrolysis of both of the acetylester groups of heroin. The enzyme displays optimum activity at pH 8.5 and appears to be a trimer of identical subunits with an M(r) or 39,000 and a native M(r) of 120,000.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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