Abstract
Good immunoprotection was afforded by A9/SEWA somatic hybrid cells in the C3H mouse/C3H Py tumour system, confirming results previously obtained in the A.SW mouse/SEWA tumour system. However, in this study the immunogenicity decreased with increasing serial subculture of the hybrid line and concomitant chromosome loss.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- DULBECCO R. Viral carcinogenesis. Cancer Res. 1961 Sep;21:975–980. [PubMed] [Google Scholar]
- Favre R., Filipczyk J., Berebbi M., Meyer G. Pouvoir immunoprotecteur d'une souche hybride contre l'inoculation de la souche tumorale parentale. Ann Immunol (Paris) 1974 Mar-Apr;125(3):491–497. [PubMed] [Google Scholar]
- Favre R., Meyer G. Comparaison entre le pouvoir protecteur du virus et de cellules transformées allogéniques dans le système virus polyome-souris. C R Acad Sci Hebd Seances Acad Sci D. 1972 Oct 16;275(16):1835–1837. [PubMed] [Google Scholar]
- Harris H., Miller O. J., Klein G., Worst P., Tachibana T. Suppression of malignancy by cell fusion. Nature. 1969 Jul 26;223(5204):363–368. doi: 10.1038/223363a0. [DOI] [PubMed] [Google Scholar]
- Meyer G., Berebbi M., Klein G. Expression of polyoma-induced antigens in low malignant hybrids derived from fusion of a polyoma-induced tumour with a fibroblast line. Nature. 1974 May 3;249(452):47–49. doi: 10.1038/249047a0. [DOI] [PubMed] [Google Scholar]
- Parkman R. Tumor hybrid cells: an immunotherapeutic agent. J Natl Cancer Inst. 1974 May;52(5):1541–1545. doi: 10.1093/jnci/52.5.1541. [DOI] [PubMed] [Google Scholar]