Abstract
Intrapleural growth of transplanted rat tumours was prevented or retarded by intrapleural administration of double-stranded RNA. A similar suppression of growth was achieved with peitoneal tumours by the intraperitoneal injection of the compound. These studies indicate the possible potential of this form of treatment of thoracic and peritoneal tumours for clinical application in the treatment of mesothelioma.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Baldwin R. W., Pimm M. V. Influence of BCG infection on growth of 3-methylcholanthrene-induced rat sarcomas. Rev Eur Etud Clin Biol. 1971 Nov;16(9):875–881. [PubMed] [Google Scholar]
- Heyes J., Catherall E. J., Harnden M. R. Antitumour evaluation of a ribonuclease resistant double-stranded RNA-polyquaternary ammonium complex (BRL 10739). Eur J Cancer. 1974 Jul;10(7):431–435. doi: 10.1016/0014-2964(74)90026-7. [DOI] [PubMed] [Google Scholar]
- Likhite V. V., Halpern B. N. The delayed rejection of tumors formed from the administration of tumor cells mixed with killed Corynebacterium parvum. Int J Cancer. 1973 Nov 15;12(3):699–704. doi: 10.1002/ijc.2910120317. [DOI] [PubMed] [Google Scholar]
- Parr I., Wheeler E., Alexander P. Similarities of the anti-tumour actions of endotoxin, lipid A and double-stranded RNA. Br J Cancer. 1973 May;27(5):370–389. doi: 10.1038/bjc.1973.45. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pimm M. V., Hopper D. G. Proceedings: Role of immunocompetence in localized BCG suppression of tumour growth. Br J Cancer. 1975 Aug;32(2):241–242. doi: 10.1038/bjc.1975.160. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Zbar B., Bernstein I. D., Rapp H. J. Suppression of tumor growth at the site of infection with living Bacillus Calmette-Guérin. J Natl Cancer Inst. 1971 Apr;46(4):831–839. [PubMed] [Google Scholar]