Skip to main content
British Journal of Cancer logoLink to British Journal of Cancer
. 1977 Feb;35(2):142–151. doi: 10.1038/bjc.1977.21

A cell line from an anaplastic transitional cell carcinoma of human urinary bladder.

S K Nayak, C O'Toole, Z H Price
PMCID: PMC2025316  PMID: 836756

Abstract

A cell line, TCCSUP, derived from an undifferentiated, Grade IV transitional cell carcinoma is described. The karyotype showed an abnormal distribution of chromosomes, with no obvious modal number. Distinct marker chromosomes were observed in both early and late in vitro passages. These cells have been subcultured over 50 times during a 20-month period. TCCSUP differs in certain morphological and immunological features from other cell lines from transitional cell carcinomas.

Full text

PDF
142

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BATTIFORA H., EISENSTEIN R., MCDONALD J. H. THE HUMAN URINARY BLADDER MUCOSA. AN ELECTRON MICROSCOPIC STUDY. Invest Urol. 1964 Jan;1:354–361. [PubMed] [Google Scholar]
  2. Bubeník J., Baresová M., Viklický V., Jakoubková J., Sainerová H., Donner J. Established cell line of urinary bladder carcinoma (T24) containing tumour-specific antigen. Int J Cancer. 1973 May;11(3):765–773. doi: 10.1002/ijc.2910110327. [DOI] [PubMed] [Google Scholar]
  3. Hakala T. R., Lange P. H. Serum induced lymphoid cell mediated cytotoxicity to human transitional cell carcinomas of the genitourinary tract. Science. 1974 May 17;184(4138):795–797. doi: 10.1126/science.184.4138.795. [DOI] [PubMed] [Google Scholar]
  4. Nelson-Rees W. A., Flandermeyer R. R., Hawthorne P. K. Banded marker chromosomes as indicators of intraspecies cellular contamination. Science. 1974 Jun 7;184(4141):1093–1096. doi: 10.1126/science.184.4141.1093. [DOI] [PubMed] [Google Scholar]
  5. O'Toole C., Nayak S., Price Z., Gilbert W. H., Waisman J. A cell line (SCABER) derived from squamous cell carcinoma of the human urinary bladder. Int J Cancer. 1976 Jun 15;17(6):707–714. doi: 10.1002/ijc.2910170604. [DOI] [PubMed] [Google Scholar]
  6. O'Toole C., Stejskal V., Perlmann P., Karlsson M. Lymphoid cells mediating tumor-specific cytotoxicity to carcinoma of the urinary bladder. Separation of the effector population using a surface marker. J Exp Med. 1974 Mar 1;139(3):457–466. doi: 10.1084/jem.139.3.457. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Price Z. H. A three-dimensional model of membrane ruffling from transmission and scanning electron microscopy of cultured monkey kidney cells (LLCMK 2 ). J Microsc. 1972 Jun;95(3):493–505. doi: 10.1111/j.1365-2818.1972.tb01053.x. [DOI] [PubMed] [Google Scholar]
  8. Rigby C. C., Franks L. M. A human tissue culture cell line from a transitional cell tumour of the urinary bladder: growth, chromosone pattern and ultrastructure. Br J Cancer. 1970 Dec;24(4):746–754. doi: 10.1038/bjc.1970.89. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Russell W. C., Newman C., Williamson D. H. A simple cytochemical technique for demonstration of DNA in cells infected with mycoplasmas and viruses. Nature. 1975 Feb 6;253(5491):461–462. doi: 10.1038/253461a0. [DOI] [PubMed] [Google Scholar]
  10. Seabright M. A rapid banding technique for human chromosomes. Lancet. 1971 Oct 30;2(7731):971–972. doi: 10.1016/s0140-6736(71)90287-x. [DOI] [PubMed] [Google Scholar]
  11. Springer E. L., Hackett A. J., Nelson-Rees W. A. Alteration of the cell membrane architecture during suspension and monolayer culturing. Int J Cancer. 1976 Mar 15;17(3):407–415. doi: 10.1002/ijc.2910170318. [DOI] [PubMed] [Google Scholar]

Articles from British Journal of Cancer are provided here courtesy of Cancer Research UK

RESOURCES