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British Journal of Cancer logoLink to British Journal of Cancer
. 1977 Sep;36(3):362–368. doi: 10.1038/bjc.1977.201

Second primary cancers in patients with tumours of the salivary glands.

P Prior, J A Waterhouse
PMCID: PMC2025415  PMID: 921892

Abstract

In a series of patients drawn from the Birmingham Regional Cancer Registry (England) with tumours of the salivary glands, a significant excess of second primary tumours was observed. For females, the excess was found mainly in breast and bronchus and, for males, in prostate and skin. In a parallel series of female breast-cancer patients, the observed number of second primary tumours in salivary glands significantly exceeded expectation. These results support the reported association between salivary gland and breast cancer, and suggest that other hormone-dependent sites are also at risk.

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Selected References

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  1. BULBROOK R. D., HAYWARD J. L., SPICER C. C., THOMAS B. S. Abnormal excretion of urinary steroids by women with early breast cancer. Lancet. 1962 Dec 15;2(7268):1238–1240. doi: 10.1016/s0140-6736(62)92812-x. [DOI] [PubMed] [Google Scholar]
  2. Berg J. W., Hutter R. V., Foote F. W., Jr The unique association between salivary gland cancer and breast cancer. JAMA. 1968 May 27;204(9):771–774. [PubMed] [Google Scholar]
  3. Blanck C., Eneroth C. M., Jakobsson P. A. Oncocytoma of the parotid gland: neoplasm or nodular hyperplasia? Cancer. 1970 Apr;25(4):919–925. doi: 10.1002/1097-0142(197004)25:4<919::aid-cncr2820250427>3.0.co;2-7. [DOI] [PubMed] [Google Scholar]
  4. Burton J. L., Cunliffe W. J., Shuster S. Increased sebum excretion in patients with breast cancer. Br Med J. 1970 Mar 14;1(5697):665–666. doi: 10.1136/bmj.1.5697.665. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Dunn J. E., Jr, Bragg K. U., Sautter C., Gardipee C. Breast cancer risk following a major salivary gland carcinoma. Cancer. 1972 May;29(5):1343–1346. doi: 10.1002/1097-0142(197205)29:5<1343::aid-cncr2820290532>3.0.co;2-y. [DOI] [PubMed] [Google Scholar]
  6. Glucksman A., Cherry C. P. The effect of sex and of sex and thyroid hormones on the induction of cancers in the salivary glands of rats. Br J Cancer. 1966 Dec;20(4):760–777. doi: 10.1038/bjc.1966.88. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Hoshino K., Lin C. D. Lethal factor released from submandibular grafts in mice. Can J Physiol Pharmacol. 1969 Apr;47(4):329–334. doi: 10.1139/y69-059. [DOI] [PubMed] [Google Scholar]
  8. Moertel C. G., Elveback L. R. The association between salivary gland cancer and breast cancer. JAMA. 1969 Oct 13;210(2):306–308. [PubMed] [Google Scholar]
  9. Newell G. R., Krementz E. T., Roberts J. D. Multiple primary neoplasms in blacks compared to whites. II. Further cancers in patients with cancer of the buccal cavity and pharynx. J Natl Cancer Inst. 1974 Mar;52(3):639–642. doi: 10.1093/jnci/52.3.639. [DOI] [PubMed] [Google Scholar]
  10. Rao L. G. Lung cancer as an endocrine disease. Nature. 1972 Jan 28;235(5335):220–222. doi: 10.1038/235220c0. [DOI] [PubMed] [Google Scholar]
  11. STERN E., HOPKINS C. E., WEINER J. M., MARMORSTON J. HORMONE EXCRETION PATTERNS IN BREAST AND PROSTATE CANCER ARE ABNORMAL. Science. 1964 Aug 14;145(3633):716–719. doi: 10.1126/science.145.3633.716. [DOI] [PubMed] [Google Scholar]
  12. Turkington R. W. Stimulation of mammary carcinoma cell proliferation by epithelial growth factor in vitro. Cancer Res. 1969 Jul;29(7):1457–1458. [PubMed] [Google Scholar]
  13. Wang D. Y., Bulbrook R. D., Guillebaud J., Lewis A. The relation between sebum production and plasma 17-oxosteroid levels in normal women and in patients with breast cancer. Eur J Cancer. 1972 Aug;8(4):381–385. doi: 10.1016/0014-2964(72)90120-x. [DOI] [PubMed] [Google Scholar]

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