Skip to main content
NCBI home page
Applied and Environmental Microbiology logoLink to Applied and Environmental Microbiology
. 1988 Apr;54(4):1063–1065. doi: 10.1128/aem.54.4.1063-1065.1988

Effects of Metals on 3-Acetyldeoxynivalenol Production by Fusarium graminearum R2118 in Submerged Cultures

Amit B Vasavada 1, Dennis P H Hsieh 1,*
PMCID: PMC202597  PMID: 16347603

Abstract

The effects of selected metals (Mg2+, Mn2+, Zn2+, and Fe2+) on 3-acetyldeoxynivalenol (3-ADN) production by Fusarium graminearum R2118 and on its mycelial growth were investigated by using a two-stage submerged-culture technique. In certain concentrations ranges, Mg2+ and Fe2+ stimulated growth but suppressed 3-ADN production; at other concentrations, Mg2+, Fe2+, and Zn2+ suppressed growth but stimulated 3-ADN production. In contrast, Mn2+ stimulated growth but totally inhibited 3-ADN production at all concentrations tested. In general, the production of 3-ADN was inversely related to the growth rate of the fungus with these metals. Mn2+ appears to be a crucial factor regulating the onset of 3-ADN biosynthesis.

Full text

PDF
1063

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BU'LOCK J. D. Intermediary metabolism and antibiotic synthesis. Adv Appl Microbiol. 1961;3:293–342. doi: 10.1016/s0065-2164(08)70514-8. [DOI] [PubMed] [Google Scholar]
  2. KALYANASUNDARAM R., SARASWATHIDEVI L. Zinc in the metabolism of Fusarium vasinfectum Atk. Nature. 1955 May 28;175(4465):945–945. doi: 10.1038/175945a0. [DOI] [PubMed] [Google Scholar]
  3. MATELES R. I., ADYE J. C. PRODUCTION OF AFLATOXINS IN SUBMERGED CULTURE. Appl Microbiol. 1965 Mar;13:208–211. doi: 10.1128/am.13.2.208-211.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Rosazza J. P., Kelleher W. J., Schwarting A. E. Production of Lysergic Acid Derivatives in Submerged Culture: IV. Inorganic Nutrition Studies with Claviceps paspali. Appl Microbiol. 1967 Nov;15(6):1270–1283. doi: 10.1128/am.15.6.1270-1283.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Shu P., Johnson M. J. The Interdependence of Medium Constituents in Citric Acid Production by Submerged Fermentation. J Bacteriol. 1948 Nov;56(5):577–585. doi: 10.1128/jb.56.5.577-585.1948. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Steenbergen S. T., Weinberg E. D. Trace metal requirements for malformin biosynthesis. Growth. 1968 Jun;32(2):125–134. [PubMed] [Google Scholar]

Articles from Applied and Environmental Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES