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. 1989 Oct;55(10):2723–2725. doi: 10.1128/aem.55.10.2723-2725.1989

Toxicity of Trichloroethylene to Pseudomonas putida F1 Is Mediated by Toluene Dioxygenase

Lawrence P Wackett 1,*, Steven R Householder 1
PMCID: PMC203151  PMID: 16348039

Abstract

Trichloroethylene was metabolically activated by toluene dioxygenase to produce toxic effects in Pseudomonas putida F1. Cytotoxicity was indicated by growth inhibition and by the covalent modification of cellular molecules in P. putida F1 exposed to [14C]trichloroethylene. With a toluene dioxygenase mutant, neither growth inhibition nor alkylation of intracellular molecules was observed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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