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. 1994 Sep;70(3):398–400. doi: 10.1038/bjc.1994.316

Evaluation of a morpholinothiolporphyrin for use in photodynamic therapy.

K W Woodburn 1, J S Hill 1, S Stylli 1, A H Kaye 1, J A Reiss 1, D R Phillips 1
PMCID: PMC2033371  PMID: 8080721

Abstract

The photonecrotic effectiveness of a morpholinothiolporphyrin derived from haematoporphyrin was measured in an animal model of cerebral glioma. The dose administered was 20 mg kg-1 and the laser dose varied from 0 to 200 J cm-2. The tumour necrosis was at least as good as that of HpD, and this therapeutic response may be attributed to the targeting of specific 'photopotent' subcellular sites.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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