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British Journal of Cancer logoLink to British Journal of Cancer
. 1995 Jan;71(1):137–139. doi: 10.1038/bjc.1995.28

The use of colour-coded and spectral Doppler ultrasound in the differentiation of benign and malignant breast lesions.

C Peters-Engl 1, M Medl 1, S Leodolter 1
PMCID: PMC2033465  PMID: 7819029

Abstract

The aim of this study was to evaluate the role of colour-coded and spectral Doppler sonography to predict the benign or malignant nature of breast lesions. A total of 112 women with mammographically suspicious breast lesions were investigated prior to surgery. Thirty-nine breast carcinomas and 73 benign lesions were evaluated for the resistance index, pulsatility index and the flow velocity. A resistance index of > or = 0.70 was characteristic of malignant tumours with a sensitivity of 82% and a specificity of 81%. The positive predictive value was 70% and the negative predictive value 89%. Doppler sonography offers one possible method for further investigation of patients with mammographic abnormalities.

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Selected References

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  1. Britton P. D., Coulden R. A. The use of duplex Doppler ultrasound in the diagnosis of breast cancer. Clin Radiol. 1990 Dec;42(6):399–401. doi: 10.1016/s0009-9260(05)80892-x. [DOI] [PubMed] [Google Scholar]
  2. Burns P. N., Halliwell M., Wells P. N., Webb A. J. Ultrasonic Doppler studies of the breast. Ultrasound Med Biol. 1982;8(2):127–143. doi: 10.1016/0301-5629(82)90092-8. [DOI] [PubMed] [Google Scholar]
  3. Cosgrove D. O., Bamber J. C., Davey J. B., McKinna J. A., Sinnett H. D. Color Doppler signals from breast tumors. Work in progress. Radiology. 1990 Jul;176(1):175–180. doi: 10.1148/radiology.176.1.2191364. [DOI] [PubMed] [Google Scholar]
  4. Dixon J. M., Walsh J., Paterson D., Chetty U. Colour Doppler ultrasonography studies of benign and malignant breast lesions. Br J Surg. 1992 Mar;79(3):259–260. doi: 10.1002/bjs.1800790325. [DOI] [PubMed] [Google Scholar]
  5. Dock W. Duplex sonography of mammary tumors: a prospective study of 75 patients. J Ultrasound Med. 1993 Feb;12(2):79–82. doi: 10.7863/jum.1993.12.2.79. [DOI] [PubMed] [Google Scholar]
  6. Dock W., Grabenwöger F., Metz V., Eibenberger K., Farrés M. T. Tumor vascularization: assessment with duplex sonography. Radiology. 1991 Oct;181(1):241–244. doi: 10.1148/radiology.181.1.1887039. [DOI] [PubMed] [Google Scholar]
  7. Folkman J. How is blood vessel growth regulated in normal and neoplastic tissue? G.H.A. Clowes memorial Award lecture. Cancer Res. 1986 Feb;46(2):467–473. [PubMed] [Google Scholar]
  8. Folkman J., Merler E., Abernathy C., Williams G. Isolation of a tumor factor responsible for angiogenesis. J Exp Med. 1971 Feb 1;133(2):275–288. doi: 10.1084/jem.133.2.275. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med. 1971 Nov 18;285(21):1182–1186. doi: 10.1056/NEJM197111182852108. [DOI] [PubMed] [Google Scholar]
  10. Jackson V. P. Duplex sonography of the breast. Ultrasound Med Biol. 1988;14 (Suppl 1):131–137. doi: 10.1016/0301-5629(88)90056-7. [DOI] [PubMed] [Google Scholar]
  11. Jellins J. Combining imaging and vascularity assessment of breast lesions. Ultrasound Med Biol. 1988;14 (Suppl 1):121–130. doi: 10.1016/0301-5629(88)90055-5. [DOI] [PubMed] [Google Scholar]
  12. Madjar H., Prömpeler H., Kommoss F., Göppinger A. Ergänzt der Farbdoppler die Mammadiagnostik? Radiologe. 1992 Nov;32(11):568–575. [PubMed] [Google Scholar]
  13. Srivastava A., Webster D. J., Woodcock J. P., Shrotria S., Mansel R. E., Hughes L. E. Role of Doppler ultrasound flowmetry in the diagnosis of breast lumps. Br J Surg. 1988 Sep;75(9):851–853. doi: 10.1002/bjs.1800750907. [DOI] [PubMed] [Google Scholar]

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