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. 1995 Nov;72(5):1312–1319. doi: 10.1038/bjc.1995.507

Cancer mortality in Indian and British ethnic immigrants from the Indian subcontinent to England and Wales.

A J Swerdlow 1, M G Marmot 1, A E Grulich 1, J Head 1
PMCID: PMC2033952  PMID: 7577489

Abstract

Risk of cancer mortality from 1973 to 1985 in persons born in the Indian subcontinent who migrated to England and Wales was analysed by ethnicity, and compared with cancer mortality in the England and Wales native population, using data from England and Wales death certificates. There were substantial highly significant raised risks in Indian ethnic migrants for cancers of the mouth and pharynx, gall bladder, and liver in each sex, larynx and thyroid in males, and oesophagus in females. There were also substantial raised risks in these migrants of each sex for non-Hodgkin's lymphoma and myeloma. For the mouth and pharynx, and liver in each sex, and gall bladder in females, there were also raised risks of lesser magnitude in British ethnic migrants. For colon and rectal cancer and cutaneous melanoma in each sex, ovarian cancer in women and bladder cancer in men, there were appreciable significantly reduced risks in the Indian ethnic migrants not shared by those of British ethnicity. Appreciable raised risks in British ethnic migrants not shared by those of Indian ethnicity occurred for nasopharyngeal cancer in males, soft tissue malignancy in both sexes and non-melanoma skin cancer in males. In migrants of both ethnicities there were appreciable significantly raised risks in each sex for leukaemia and decreased risks in each sex for gastric cancer, for lung cancer except in females of British ethnicity and in males for testicular cancer. The results suggest the need for public health measures to combat the high risks of oral and pharyngeal cancers and liver cancer in the Indian ethnic immigrant population of England and Wales, by prevention of betel quid chewing and hepatitis transmission respectively. The data also imply that early exposures or early acquired behaviours in India, or exposures during migration, may increase the risk of leukaemia and reduce the risks of gastric and testicular cancers in the migrants irrespective of their ethnicity. Aetiological studies would be worthwhile to investigate the reasons for the sizeable decreased risk of colon and rectal cancer and increased risk of gall bladder cancer in each sex and the increased risk of thyroid and laryngeal cancer in males and oesophageal cancer in females of Indian ethnicity but not of British ethnicity who have migrated from the Indian subcontinent.

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Selected References

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  1. Balarajan R., Bulusu L., Adelstein A. M., Shukla V. Patterns of mortality among migrants to England and Wales from the Indian subcontinent. Br Med J (Clin Res Ed) 1984 Nov 3;289(6453):1185–1187. doi: 10.1136/bmj.289.6453.1185. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Boxall E., Skidmore S., Evans C., Nightingale S. The prevalence of hepatitis B and C in an antenatal population of various ethnic origins. Epidemiol Infect. 1994 Dec;113(3):523–528. doi: 10.1017/s0950268800068539. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Boyd J. T., Doll R., Gurd C. H. Cancer incidence in Fiji. Int J Epidemiol. 1973 Summer;2(2):177–187. doi: 10.1093/ije/2.2.177. [DOI] [PubMed] [Google Scholar]
  4. Donaldson L. J., Clayton D. G. Occurrence of cancer in Asians and non-Asians. J Epidemiol Community Health. 1984 Sep;38(3):203–207. doi: 10.1136/jech.38.3.203. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Donaldson L. J., Taylor J. B. Patterns of Asian and non-Asian morbidity in hospitals. Br Med J (Clin Res Ed) 1983 Mar 19;286(6369):949–951. doi: 10.1136/bmj.286.6369.949. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Grulich A. E., McCredie M., Coates M. Cancer incidence in Asian migrants to New South Wales, Australia. Br J Cancer. 1995 Feb;71(2):400–408. doi: 10.1038/bjc.1995.82. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Jussawalla D. J., Deshpande V. A. Evaluation of cancer risk in tobacco chewers and smokers: an epidemiologic assessment. Cancer. 1971 Jul;28(1):244–252. doi: 10.1002/1097-0142(197107)28:1<244::aid-cncr2820280150>3.0.co;2-h. [DOI] [PubMed] [Google Scholar]
  8. MANTEL N., HAENSZEL W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst. 1959 Apr;22(4):719–748. [PubMed] [Google Scholar]
  9. MARSDEN A. T. The geographical pathology of cancer in Malaya. Br J Cancer. 1958 Jun;12(2):161–176. doi: 10.1038/bjc.1958.20. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Matheson L. M., Dunnigan M. G., Hole D., Gillis C. R. Incidence of colo-rectal, breast and lung cancer in a Scottish Asian population. Health Bull (Edinb) 1985 Sep;43(5):245–249. [PubMed] [Google Scholar]
  11. McKeigue P. M., Karmi G. Alcohol consumption and alcohol-related problems in Afro-Caribbeans and south Asians in the United Kingdom. Alcohol Alcohol. 1993 Jan;28(1):1–10. [PubMed] [Google Scholar]
  12. McKeigue P. M., Shah B., Marmot M. G. Relation of central obesity and insulin resistance with high diabetes prevalence and cardiovascular risk in South Asians. Lancet. 1991 Feb 16;337(8738):382–386. doi: 10.1016/0140-6736(91)91164-p. [DOI] [PubMed] [Google Scholar]
  13. Miettinen O. S., Wang J. D. An alternative to the proportionate mortality ratio. Am J Epidemiol. 1981 Jul;114(1):144–148. doi: 10.1093/oxfordjournals.aje.a113161. [DOI] [PubMed] [Google Scholar]
  14. Nicoll A., Bassett K., Ulijaszek S. J. What's in a name? Accuracy of using surnames and forenames in ascribing Asian ethnic identity in English populations. J Epidemiol Community Health. 1986 Dec;40(4):364–368. doi: 10.1136/jech.40.4.364. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. PAYMASTER J. C. CANCER AND ITS DISTRIBUTION IN INDIA. Cancer. 1964 Aug;17:1026–1034. doi: 10.1002/1097-0142(196408)17:8<1026::aid-cncr2820170809>3.0.co;2-4. [DOI] [PubMed] [Google Scholar]
  16. Robins J., Breslow N., Greenland S. Estimators of the Mantel-Haenszel variance consistent in both sparse data and large-strata limiting models. Biometrics. 1986 Jun;42(2):311–323. [PubMed] [Google Scholar]
  17. SARMA S. N. A study into the incidence and etiology of cancer of the larynx and adjacent parts in Assam. Indian J Med Res. 1958 May;46(3):525–533. [PubMed] [Google Scholar]
  18. Schonland M., Bradshaw E. Cancer in the natal African and Indian 1964-66. Int J Cancer. 1968 Mar 15;3(2):304–316. doi: 10.1002/ijc.2910030216. [DOI] [PubMed] [Google Scholar]

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