Abstract
Filtrates of Fusarium sambucinum NRRL 13495 grown in a stagnant culture for 9 days contained up to 458 +/- 60 (mean +/- standard error; n = 3) mg of 4,15-diacetoxyscirpenol per liter depending on culture conditions. Extraction with ethyl acetate, chromatography on a column of silica gel, and crystallization from mixtures of ethyl acetate and hexane provided pure material in 96% yield.
Full text
PDF


Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Abbas H. K., Mirocha C. J., Shier W. T. Mycotoxins produced from fungi isolated from foodstuffs and soil: comparison of toxicity in fibroblasts and rat feeding tests. Appl Environ Microbiol. 1984 Sep;48(3):654–661. doi: 10.1128/aem.48.3.654-661.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Allen N. K., Jevne R. L., Mirocha C. J., Lee Y. W. The effect of a Fusarium roseum culture and diacetoxyscirpenol on reproduction of White Leghorn females. Poult Sci. 1982 Nov;61(11):2172–2175. doi: 10.3382/ps.0612172. [DOI] [PubMed] [Google Scholar]
- Burditt S. J., Hagler W. M., Jr, Hutchins J. E., Hamilton P. B. Models of feed refusal syndrome in poultry. Poult Sci. 1983 Nov;62(11):2158–2163. doi: 10.3382/ps.0622158. [DOI] [PubMed] [Google Scholar]
- Dutton M. F., Ehrlich K., Bennett J. W. Biosynthetic relationship among aflatoxins B1, B2, M1, and M2. Appl Environ Microbiol. 1985 Jun;49(6):1392–1395. doi: 10.1128/aem.49.6.1392-1395.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ghosal S., Chakrabarti D. K., Basu Chaudhary K. C. Toxic substances produced by Fusarium I: trichothecene derivatives from two strains of Fusarium oxysporum f. sp. carthami. J Pharm Sci. 1976 Jan;65(1):160–161. doi: 10.1002/jps.2600650145. [DOI] [PubMed] [Google Scholar]
- Gilgan M. W., Smalley E. B., Strong F. M. Isolation and partial characterization of a toxin from Fusarium tricinctum on moldy corn. Arch Biochem Biophys. 1966 Apr;114(1):1–3. doi: 10.1016/0003-9861(66)90297-9. [DOI] [PubMed] [Google Scholar]
- Hoerr F. J., Carlton W. W., Yagen B., Joffe A. Z. Mycotoxicosis caused by either T-2 toxin or diacetoxyscirpenol in the diet of broiler chickens. Fundam Appl Toxicol. 1982 May-Jun;2(3):121–124. doi: 10.1016/s0272-0590(82)80092-4. [DOI] [PubMed] [Google Scholar]
- Ishii K., Pathre S. V., Mirocha C. J. Two new trichothecenes produced by Fusarium roseum. J Agric Food Chem. 1978 May-Jun;26(3):649–653. doi: 10.1021/jf60217a030. [DOI] [PubMed] [Google Scholar]
- Jarvis B. B., Lee Y. W., Yatawara C. S., Mazzocchi D. B., Flippen-Anderson J. L., Gilardi R., George C. 7 alpha-hydroxytrichodermol, a new trichothecene from Myrothecium roridum. Appl Environ Microbiol. 1985 Nov;50(5):1225–1228. doi: 10.1128/aem.50.5.1225-1228.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mirocha C. J., Pathre S. V., Schauerhamer B., Christensen C. M. Natural occurrence of Fusarium toxins in feedstuff. Appl Environ Microbiol. 1976 Oct;32(4):553–556. doi: 10.1128/aem.32.4.553-556.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pathre S. V., Mirocha C. J., Christensen C. M., Behrens J. Monoacetoxyscirpenol. A new mycotoxin produced by Fusarium roseum Gibbosum. J Agric Food Chem. 1976 Jan-Feb;24(1):97–103. doi: 10.1021/jf60203a053. [DOI] [PubMed] [Google Scholar]
- Scott P. M., Lawrence J. W., van Walbeek W. Detection of mycotoxins by thin-layer chromatography: application to screening of fungal extracts. Appl Microbiol. 1970 Nov;20(5):839–842. doi: 10.1128/am.20.5.839-842.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ueno Y., Sato N., Ishii K., Sakai K., Tsunoda H. Biological and chemical detection of trichothecene mycotoxins of Fusarium species. Appl Microbiol. 1973 Apr;25(4):699–704. doi: 10.1128/am.25.4.699-704.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Vidal D., Chapon P., Creach O., Fontanges R. Influence de la température sur la production de diacétoxyscirpénol et sur la sporulation d'une culture liquide de Fusarium sambucinum. C R Seances Soc Biol Fil. 1984;178(5):518–525. [PubMed] [Google Scholar]
