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. 1993 Mar;175(6):1847–1852. doi: 10.1128/jb.175.6.1847-1852.1993

The unstable melC operon of Streptomyces antibioticus is codeleted with a Tn4811-homologous locus.

T W Yu 1, C W Chen 1
PMCID: PMC203993  PMID: 8383668

Abstract

The melC operon of Streptomyces antibioticus is unstable, undergoing frequent spontaneous deletions. All the delta melC mutants analyzed also lost 2-kb V1 DNA, which contained two open reading frames (ORFs) homologous to ORF4 (a putative oxidoreductase gene) and ORF5 (a putative AraC-type regulatory gene) of Tn4811. The two ORFs may constitute an accessory unit of a different transposon.

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Selected References

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