Correction for Bauer et al., A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment

BIOCHEMISTRY. For the article “A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment,” by Jacob Bauer, Guangxin Xing, Haruhiko Yagi, Jane M. Sayer, Donald M. Jerina and Hong Ling, which appeared in issue 38, September 18, 2007, of Proc Natl Acad Sci USA (104:14905–14910; first published September 11, 2007; 10.1073/pnas.0700717104), the authors note that torsion angles appear incorrectly in two instances. On page 14906, right column, second full paragraph, beginning on line 4, “In the enzyme–substrate complex, the conformation of the adduct with χ, α′, and β′ torsion angles (Fig. 1A) of −153.0, −160.0, and 161.7, respectively, does not lie in a low-energy region as predicted for the corresponding nucleoside adduct in the absence of an enzyme (23)” should instead read: “In the enzyme–substrate complex, the conformation of the adduct with χ, α′, and β′ torsion angles (Fig. 1A) of −153.0°, −160.7°, and −106.0°, respectively, lies in a low-energy region as predicted for the corresponding nucleoside adduct in the absence of an enzyme (23).” In addition, on page 14908, left column, first full paragraph, beginning on line 18, “This conformation of BP–dG (with χ, α′, and β′ torsion angles of 87.0, −100.0, and 179.0, respectively) is energetically unfavorable based on molecular simulation (23)” should instead read: “This conformation of BP–dG with χ, α′, and β′ torsion angles of 87.2°, −179.6°, and −100.2°, respectively, is not in the most energetically favorable form based on molecular simulation (23).” These errors do not affect the conclusions of the article.