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. 1982 Aug;63(4):362–368.

Lymphocyte Chemotaxis in Inflammation. IV. Isolation of Lymphocyte Chemotactic factors from PPD-induced Delayed Hypersensitivity Skin Reaction Site in the Guinea-pig. with Special Reference to a Factor Chemotactic for B Cells

Y Shimokawa, S Harita, Y Higuchi, H Hayashi
PMCID: PMC2040653  PMID: 6983888

Abstract

Lymphocyte chemotactic factors were extracted from PPD-induced delayed hypersensitivity skin reaction sites in guinea-pigs. The presence of 3 chemotactic factors (LCF-a, LCF-b and LCF-c) was suggested by gel filtration on Sephadex G100. LCF-a was purified by gel filtration on Sephadex G-15 followed by peptide mapping. This substance was considered to be a thermostable and dialysable peptide; it appeared to be effective for B cells but not for T cells.

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Selected References

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