Skip to main content
British Journal of Experimental Pathology logoLink to British Journal of Experimental Pathology
. 1977 Jun;58(3):273–280.

A severe necrotic enterotoxin produced by certain food, food poisoning and other clinical isolates of Bacillus cereus.

P C Turnbull, J F Nottingham, A C Ghosh
PMCID: PMC2041137  PMID: 405982

Abstract

The ability of certain strains of Bacillus cereus consistently to elaborate a filterable non-dialysable toxin capable of causing severe disruption and necrosis of the intestinal mucosa and submucosa is confirmed. This property is not universal to all B. cereus strains and different degrees of production of this toxin are exhibited by the different strains which produce it. The necrotic effect is produced by whole-cell cultures of the toxin producing strains in broth and in boiled rice. Some characteristics of this necrotic toxin are described and its relationship with the diarrhoeal and other known B. cereus toxins is discussed.

Full text

PDF

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Gilbert R. J., Stringer M. F., Peace T. C. The survival and growth of Bacillus cereus in boiled and fried rice in relation to outbreaks of food poisoning. J Hyg (Lond) 1974 Dec;73(3):433–444. doi: 10.1017/s0022172400042790. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Glatz B. A., Goeppert J. M. Extracellular factor synthesized by Bacillus cereus which evokes a dermal reaction in guinea pigs. Infect Immun. 1973 Jul;8(1):25–29. doi: 10.1128/iai.8.1.25-29.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Melling J., Capel B. J., Turnbull P. C., Gilbert R. J. Identification of a novel enterotoxigenic activity associated with Bacillus cereus. J Clin Pathol. 1976 Oct;29(10):938–940. doi: 10.1136/jcp.29.10.938. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. O'Brien A. D., Kapral F. A. Increased cyclic adenosine 3',5'-monophosphate content in guinea pig ileum after exposure to Staphylococcus aureus delta-toxin. Infect Immun. 1976 Jan;13(1):152–162. doi: 10.1128/iai.13.1.152-162.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Rowe B., Taylor J., Bettelheim K. A. An investigation of traveller's diarrhoea. Lancet. 1970 Jan 3;1(7636):1–5. doi: 10.1016/s0140-6736(70)90520-9. [DOI] [PubMed] [Google Scholar]
  6. Speer M. E., Taber L. H., Yow M. D., Rudolph A. J., Urteaga J., Waller S. Fulminant neonatal sepsis and necrotizing enterocolitis associated with a "nonenteropathogenic" strain of Escherichia coli. J Pediatr. 1976 Jul;89(1):91–95. doi: 10.1016/s0022-3476(76)80939-0. [DOI] [PubMed] [Google Scholar]
  7. Spira W. M., Goepfert J. M. Biological characteristics of an enterotoxin produced by Bacillus cereus. Can J Microbiol. 1975 Aug;21(8):1236–1246. doi: 10.1139/m75-185. [DOI] [PubMed] [Google Scholar]
  8. Taylor A. J., Gilbert R. J. Bacillus cereus food poisoning: a provisional serotyping scheme. J Med Microbiol. 1975 Nov;8(4):543–550. doi: 10.1099/00222615-8-4-543. [DOI] [PubMed] [Google Scholar]
  9. Turnbull P. C. Studies on the production of enterotoxins by Bacillus cereus. J Clin Pathol. 1976 Oct;29(10):941–948. doi: 10.1136/jcp.29.10.941. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from British journal of experimental pathology are provided here courtesy of Wiley

RESOURCES