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. 1978 Apr;59(2):190–195.

Association of foetal wastage with influenza infection during ferret pregnancy.

M H Collie, C Sweet, D Cavanagh, H Smith
PMCID: PMC2041328  PMID: 656319

Abstract

Inoculation of influenza virus into pregnant ferrets during the late gestational period was investigated. Foetal resorption followed intracardial inoculation of a large dose of influenza virus (10(9.4) EBID50) and a 100-fold lower dose caused lower litter sizes at birth. The possible role of fever in foetal resorptions was largely discounted by 2 observations: a non-pyrexic dose inoculated intracardially into the pregnant ferret still had detrimental effects on foetal viability; influenza virus inoculated intranasally caused a pyrexia but did not affect the progeny. The potential of the ferret as a model for studying the possible adverse effects of influenza during pregnancy is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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