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. 1980 Oct;61(5):497–504.

Ultrastructural observations on the pathogenesis of aspirin-induced gastric erosions.

P G Robins
PMCID: PMC2041530  PMID: 7448118

Abstract

It is shown by transmission electron-microscopy that the first structural change in rats, following a dose of aspirin, is to the basement membrane of the endothelial cell of the capillary and post-capillary venule. This leads to the breakdown of small blood vessels before any other cytolytic effect. This is a focal effect and it is proposed that the erosion develops as an ischaemic infarct.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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