Skip to main content
British Journal of Pharmacology logoLink to British Journal of Pharmacology
. 1979 May;66(1):5–6.

An effect of haloperidol on the increased food and water intake induced in rabbits by 2-deoxy-D-glucose.

J Anderson, D F Sharman, D B Stephens
PMCID: PMC2043779  PMID: 454950

Abstract

Rabbits treated with 2-deoxy-D-glucose (2DG) (300 mg/kg) show an increased intake of food and water. Pretreatment with haloperidol (1 mg/kg) abolishes the increase in water intake but does not prevent the increase in food intake.

Full text

PDF
5

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Andén N. E., Butcher S. G., Corrodi H., Fuxe K., Ungerstedt U. Receptor activity and turnover of dopamine and noradrenaline after neuroleptics. Eur J Pharmacol. 1970;11(3):303–314. doi: 10.1016/0014-2999(70)90006-3. [DOI] [PubMed] [Google Scholar]
  2. Antelman S. M., Szechtman H., Chin P., Fisher A. E. Tail pinch-induced eating, gnawing and licking behavior in rats: dependence on the nigrostriatal dopamine system. Brain Res. 1975 Dec 5;99(2):319–337. doi: 10.1016/0006-8993(75)90032-3. [DOI] [PubMed] [Google Scholar]
  3. BROWN J. Effects of 2-deoxyglucose on carbohydrate metablism: review of the literature and studies in the rat. Metabolism. 1962 Oct;11:1098–1112. [PubMed] [Google Scholar]
  4. Bylund D. B., Snyder S. H. Beta adrenergic receptor binding in membrane preparations from mammalian brain. Mol Pharmacol. 1976 Jul;12(4):568–580. [PubMed] [Google Scholar]
  5. Fitzsimons J. T., Setler P. E. The relative importance of central nervous catecholaminergic and cholinergic mechanisms in drinking in response to antiotensin and other thirst stimuli. J Physiol. 1975 Sep;250(3):613–631. doi: 10.1113/jphysiol.1975.sp011073. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Horton R. W., Meldrum B. S., Bachelard H. S. Enzymic and cerebral metabolic effects of 2-deoxy-D-glucose. J Neurochem. 1973 Sep;21(3):507–520. doi: 10.1111/j.1471-4159.1973.tb05996.x. [DOI] [PubMed] [Google Scholar]
  7. Katovich M. J., Fregly M. J. Mediation of isoproterenol-induced thirst in rats by beta2-adrenergic receptors. Can J Physiol Pharmacol. 1978 Jun;56(3):465–470. doi: 10.1139/y78-069. [DOI] [PubMed] [Google Scholar]
  8. Russell P. J., Mogenson G. J. Drinking and feeding induced by jugular and portal infusions of 2-deoxy-D-glucose. Am J Physiol. 1975 Oct;229(4):1014–1018. doi: 10.1152/ajplegacy.1975.229.4.1014. [DOI] [PubMed] [Google Scholar]
  9. Smith G. P., Epstein A. N. Increased feeding in response to decreased glucose utilization in the rat and monkey. Am J Physiol. 1969 Oct;217(4):1083–1087. doi: 10.1152/ajplegacy.1969.217.4.1083. [DOI] [PubMed] [Google Scholar]

Articles from British Journal of Pharmacology are provided here courtesy of The British Pharmacological Society

RESOURCES