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. 1988 Nov;54(11):2856–2858. doi: 10.1128/aem.54.11.2856-2858.1988

Comparative mycobactericidal efficacy of chemical disinfectants in suspension and carrier tests.

M Best 1, S A Sattar 1, V S Springthorpe 1, M E Kennedy 1
PMCID: PMC204385  PMID: 3145713

Abstract

The efficacy of nine disinfectants on Mycobacterium smegmatis was tested in the presence of sputum, using quantitative suspension and carrier tests. Glutaraldehyde, povidone iodine, and chlorhexidine gluconate produced at least a 6-log10 reduction in CFU in all tests. Four disinfectants (sodium dichloroisocyanurate, phenol, ethanol, and sodium hypochlorite) were not as effective in the carrier tests as in the suspension tests; this difference ranged from a 1- to a 5-log10 reduction in CFU. The efficacy of ethanol and sodium hypochlorite was further reduced (3- and 1-log10 reductions in CFU, respectively) in the presence of sputum. The quaternary ammonium compound and iodophor were ineffective in all tests. The findings of this study demonstrate the need for a quantitative carrier test such as the one presented here.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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