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. 1988 Nov;54(11):2862–2865. doi: 10.1128/aem.54.11.2862-2865.1988

Cultivation of cottontail rabbit epidermal (Sf1Ep) cells on microcarrier beads and their use for suspension cultivation of Treponema pallidum subsp. pallidum.

B S Riley 1, D L Cox 1
PMCID: PMC204387  PMID: 3063209

Abstract

In vitro propagation of Treponema pallidum can be achieved by cocultivation with Sf1Ep cells. This study had two objectives: (i) to achieve suspension cultivation of Sf1Ep cells and (ii) to develop procedures for achieving the replication of T. pallidum in those cell cultures. Seven suspension cultures of Sf1Ep cells yielded an average of 7.2 x 10(8) T. pallidum (36-fold increase) after 12 days.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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