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. 1979 Nov;67(3):387–391. doi: 10.1111/j.1476-5381.1979.tb08692.x

Concomitant development of [3H]-dopamine and [3H]-5-hydroxytryptamine uptake systems in rat brain regions.

D F Kirksey, T A Slotkin
PMCID: PMC2043935  PMID: 497539

Abstract

1 Synaptosomal uptake mechanisms of 5-hydroxytryptamine and dopamine were examined in cerebral cortex, corpus striatum and midbrain plus brainstem of developing rats. 2 In all regions, there was generally a parallel biphasic development of both uptake systems; the most rapid increases occurred in the first two weeks postpartum, followed by a slower rate of increase. 3 Kinetic studies with dopamine indicated that the maturation involved increases in maximal uptake without a change in the substrate Km, suggesting that there is a change in the number or terminals but not in the uptake system per se.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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