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. 1980 May;69(1):6–7. doi: 10.1111/j.1476-5381.1980.tb10874.x

Impromidine (SK & F 92676) acts as a partial agonist on the isolated whole stomach of the rat.

M Parsons, C Sykes
PMCID: PMC2044178  PMID: 6445767

Abstract

The present secretory studies on the isolated stomach of the rat provide evidence that impromidine acts as a partial agonist at the histamine H2-receptors. It was found to be 100 times more potent than histamine but with a maximal response only 50% that obtained with histamine.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bunce K. T., Parsons M. E. A quantitative study of metiamide, a histamine H2-antagonist, on the isolated whole rat stomach. J Physiol. 1976 Jun;258(2):453–465. doi: 10.1113/jphysiol.1976.sp011430. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Durant G. J., Duncan W. A., Ganellin C. R., Parsons M. E., Blakemore R. C., Rasmussen A. C. Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors. Nature. 1978 Nov 23;276(5686):403–405. doi: 10.1038/276403a0. [DOI] [PubMed] [Google Scholar]

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