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. 1983 Mar;78(3):452–454. doi: 10.1111/j.1476-5381.1983.tb08804.x

delta 9-Tetrahydrocannabinol reduces brain regional histamine concentrations.

M R Fennessy, S J Lewis, D A Taylor, A J Verberne
PMCID: PMC2044729  PMID: 6301598

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Barbin G., Garbarg M., Schwartz J. C., Storm-Mathisen J. Histamine synthesizing afferents to the hippocampal region. J Neurochem. 1976 Feb;26(2):259–263. doi: 10.1111/j.1471-4159.1976.tb04474.x. [DOI] [PubMed] [Google Scholar]
  2. Bhattacharyya A. K., Aulakh C. S., Pradhan S., Ghosh P., Pradhan S. N. Behavioral and neurochemical effects of delta 9-tetrahydrocannabinol in rats. Neuropharmacology. 1980 Jan;19(1):87–95. doi: 10.1016/0028-3908(80)90170-7. [DOI] [PubMed] [Google Scholar]
  3. Burstein S., Hunter S. The biochemistry of the cannabinoids. Rev Pure Appl Pharmacol Sci. 1981 Apr-Jun;2(2):155–226. [PubMed] [Google Scholar]
  4. Fenimore D. C., Loy P. R. Injectible dispersion of delta 9-tetrahydrocannabinol in saline using polyvinylpyrrolidone. J Pharm Pharmacol. 1971 Apr;23(4):310–310. doi: 10.1111/j.2042-7158.1971.tb08667.x. [DOI] [PubMed] [Google Scholar]
  5. Fennessy M. R., Taylor D. A. The effect of delta9-tetrahydrocannabinol on body temperature and brain amine concentrations in the rat at differnt ambient temperatures. Br J Pharmacol. 1977 May;60(1):65–71. doi: 10.1111/j.1476-5381.1977.tb16748.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Garbarg M., Barbin G., Feger J., Schwartz J. C. Histaminergic pathway in rat brain evidenced by lesions of the medial forebrain bundle. Science. 1974 Nov 29;186(4166):833–835. doi: 10.1126/science.186.4166.833. [DOI] [PubMed] [Google Scholar]
  7. Glick S. D., Crane L. A. Opiate-like and abstinence-like effects of intracerebral histamine administration in rats. Nature. 1978 Jun 15;273(5663):547–549. doi: 10.1038/273547a0. [DOI] [PubMed] [Google Scholar]
  8. Glowinski J., Iversen L. L. Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain. J Neurochem. 1966 Aug;13(8):655–669. doi: 10.1111/j.1471-4159.1966.tb09873.x. [DOI] [PubMed] [Google Scholar]
  9. Hosko M. J., Schmeling W. T., Hardman H. F. Evidence for a caudal brainstem site of action for cannabinoid induced hypothermia. Brain Res Bull. 1981 Mar;6(3):251–258. doi: 10.1016/s0361-9230(81)80055-x. [DOI] [PubMed] [Google Scholar]
  10. Kollonitsch J., Perkins L. M., Patchett A. A., Doldouras G. A., Marburg S., Duggan D. E., Maycock A. L., Aster S. D. Selective inhibitors of biosynthesis of aminergic neurotransmitters. Nature. 1978 Aug 31;274(5674):906–908. doi: 10.1038/274906a0. [DOI] [PubMed] [Google Scholar]
  11. Lewis S. J., Fennessy M. R., Laska F. J., Taylor D. A. A modified method for the isolation and determination of brain histamine using the Bio-Rex 70. Agents Actions. 1980 Jun;10(3):197–206. doi: 10.1007/BF02025936. [DOI] [PubMed] [Google Scholar]
  12. Lomax P., Green M. D. Histaminergic neurons in the hypothalamic thermoregulatory pathways. Fed Proc. 1981 Nov;40(13):2741–2745. [PubMed] [Google Scholar]
  13. Martres M. P., Baudry M., Schwartz J. C. Histamine synthesis in the developing rat brain: evidence for a multiple compartmentation. Brain Res. 1975 Jan 10;83(2):261–275. doi: 10.1016/0006-8993(75)90935-x. [DOI] [PubMed] [Google Scholar]
  14. Mazurkiewicz-Kwilecki I. M., Filczewski M. The effects of chronic treatment with delta 9-tetrahydrocannabinol on catecholamine synthesis in the rat. Psychopharmacologia. 1973 Oct 23;33(1):71–79. doi: 10.1007/BF00428794. [DOI] [PubMed] [Google Scholar]
  15. Mechoulam R., Lander N., Varkony T. H., Kimmel I., Becker O., Ben-Zvi Z., Edery H., Porath G. Stereochemical requirements for cannabinoid activity. J Med Chem. 1980 Oct;23(10):1068–1072. doi: 10.1021/jm00184a002. [DOI] [PubMed] [Google Scholar]
  16. Revuelta A. V., Cheney D. L., Costa E., Lander N., Mechoulam R. Reduction of hippocampal acetylcholine turnover in rats treated with (-)-delta 8-tetrahydrocannabinol and its 1',2'-dimethyl-heptyl homolog. Brain Res. 1980 Aug 18;195(2):445–452. doi: 10.1016/0006-8993(80)90078-5. [DOI] [PubMed] [Google Scholar]
  17. Revuelta A. V., Cheney D. L., Wood P. L., Costa E. GABAergic mediation in the inhibition of hippocampal acetylcholine turnover rate elicited by delta 9-tetrahydrocannabinol. Neuropharmacology. 1979 Jun;18(6):525–530. doi: 10.1016/0028-3908(79)90095-9. [DOI] [PubMed] [Google Scholar]
  18. Schwartz J. C., Pollard H., Quach T. T. Histamine as a neurotransmitter in mammalian brain: neurochemical evidence. J Neurochem. 1980 Jul;35(1):26–33. doi: 10.1111/j.1471-4159.1980.tb12485.x. [DOI] [PubMed] [Google Scholar]
  19. Taylor D. A., Fennessy M. R. Biphasic nature of the effects of delta9-tetrahydrocannabinol on body temperature and brain amines of the rat. Eur J Pharmacol. 1977 Nov 15;46(2):93–99. doi: 10.1016/0014-2999(77)90244-8. [DOI] [PubMed] [Google Scholar]
  20. Taylor D. A., Fennessy M. R. Relationship between body temperature and brain monoamines during the development of tolerance to delat9-tetrahydrocannabinol in the rat. Psychopharmacology (Berl) 1978 Apr 11;56(3):279–285. doi: 10.1007/BF00432850. [DOI] [PubMed] [Google Scholar]
  21. Taylor K. M., Snyder S. H. Dynamics of the regulation of histamine levels in mouse brain. J Neurochem. 1972 Feb;19(2):341–354. doi: 10.1111/j.1471-4159.1972.tb01344.x. [DOI] [PubMed] [Google Scholar]
  22. Tuomisto L., Tuomisto J., Walaszek E. J. Uptake of histamine by rabbit hypothalamic slices. Med Biol. 1975 Feb;53(1):40–46. [PubMed] [Google Scholar]

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