Skip to main content
NCBI home page
The American Journal of Pathology logoLink to The American Journal of Pathology
. 1971 Jun;63(3):443–462.

An analysis of the effects of skin reactive factor released from lymphoid cells by concanavalin A in vivo.

H J Schwartz, P J Catanzaro, M A Leon
PMCID: PMC2047482  PMID: 5581232

Full text

PDF
443

Images in this article

460Fig 6A
on p.460
459Fig 5C
on p.459
455Fig 1A
on p.455
455Fig 1B
on p.455
456Fig 2
on p.456
456Fig 3A
on p.456
457Fig 3B
on p.457
457Fig 4
on p.457
461Fig 6B and C
on p.461
458Fig 5A and B
on p.458

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Aström K. E., Webster H. D., Arnason B. G. The initial lesion in experimental allergic neuritis. A phase and electron microscopic study. J Exp Med. 1968 Sep 1;128(3):469–495. doi: 10.1084/jem.128.3.469. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BOUGHTON B., SPECTOR W. G. Histology of the tuberculin reaction in guinea-pigs. J Pathol Bacteriol. 1963 Apr;85:371–381. doi: 10.1002/path.1700850215. [DOI] [PubMed] [Google Scholar]
  3. Bennett B., Bloom B. R. Reactions in vivo and in vitro produced by a soluble substance associated with delayed-type hypersensitivity. Proc Natl Acad Sci U S A. 1968 Mar;59(3):756–762. doi: 10.1073/pnas.59.3.756. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Bloom B. R., Bennett B. Macrophages and delayed-type hypersensitivity. Semin Hematol. 1970 Apr;7(2):215–224. [PubMed] [Google Scholar]
  5. Bloom B. R., Bennett B. Mechanism of a reaction in vitro associated with delayed-type hypersensitivity. Science. 1966 Jul 1;153(3731):80–82. doi: 10.1126/science.153.3731.80. [DOI] [PubMed] [Google Scholar]
  6. David J. R. Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction. Proc Natl Acad Sci U S A. 1966 Jul;56(1):72–77. doi: 10.1073/pnas.56.1.72. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Dumonde D. C., Wolstencroft R. A., Panayi G. S., Matthew M., Morley J., Howson W. T. "Lymphokines": non-antibody mediators of cellular immunity generated by lymphocyte activation. Nature. 1969 Oct 4;224(5214):38–42. doi: 10.1038/224038a0. [DOI] [PubMed] [Google Scholar]
  8. GELL P. G., BENACERRAF B. Studies on hypersensitivity. IV. The relationship between contact and delayed sensitivity: a study of the specificity of cellular immune reactions. J Exp Med. 1961 Mar 1;113:571–585. doi: 10.1084/jem.113.3.571. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. GELL P. G., HINDE I. T. Observations on the histology of the Arthus reaction and its relation to other known types of skin hypersensitivity. Int Arch Allergy Appl Immunol. 1954;5(1):23–46. doi: 10.1159/000228084. [DOI] [PubMed] [Google Scholar]
  10. GESNER B. M., GINSBURG V. EFFECT OF GLYCOSIDASES ON THE FATE OF TRANSFUSED LYMPHOCYTES. Proc Natl Acad Sci U S A. 1964 Sep;52:750–755. doi: 10.1073/pnas.52.3.750. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. HELMKAMP R. W., GOODLAND R. L., BALE W. F., SPAR I. L., MUTSCHLER L. E. High specific activity iodination of gamma-globulin with iodine-131 monochloride. Cancer Res. 1960 Nov;20:1495–1500. [PubMed] [Google Scholar]
  12. Kind L. S., Petersen W. A. Concanavalin A in vivo: induction of hemorrhagic skin lesions (Arthus-like reactions) in mice. Science. 1968 Apr 19;160(3825):312–313. doi: 10.1126/science.160.3825.312. [DOI] [PubMed] [Google Scholar]
  13. Leon M. A. Concanavalin A reaction with human normal immunoglobulin G and myeloma immunoglobulin G. Science. 1967 Dec 8;158(3806):1325–1326. doi: 10.1126/science.158.3806.1325. [DOI] [PubMed] [Google Scholar]
  14. McFarland W., Heilman D. H., Moorhead J. F. Functional anatomy of the lymphocyte in immunological reactions in vitro. J Exp Med. 1966 Nov 1;124(5):851–858. doi: 10.1084/jem.124.5.851. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. PAZ R. A., SPECTOR W. G. The mononuclear-cell response to injury. J Pathol Bacteriol. 1962 Jul;84:85–103. doi: 10.1002/path.1700840111. [DOI] [PubMed] [Google Scholar]
  16. Pick E., Brostoff J., Krejci J., Turk J. L. Interaction between "sensitized lymphocytes" and antigen in vitro. II. Mitogen-induced release of skin reactive and macrophage migration inhibitory factors. Cell Immunol. 1970 May;1(1):92–109. doi: 10.1016/0008-8749(70)90063-8. [DOI] [PubMed] [Google Scholar]
  17. Pick E., Krejcí J., Turk J. L. Release of skin reactive factor from guinea-pig lymphocytes by mitogens. Nature. 1970 Jan 17;225(5229):236–238. doi: 10.1038/225236a0. [DOI] [PubMed] [Google Scholar]
  18. Schwartz H. J., Leon M. A., Pelley R. P. Concanavalin A-induced release of skin-reactive factor from lymphoid cells. J Immunol. 1970 Jan;104(1):265–268. [PubMed] [Google Scholar]
  19. Spector W. G. Histology of allergic inflammation. Br Med Bull. 1967 Jan;23(1):35–38. doi: 10.1093/oxfordjournals.bmb.a070513. [DOI] [PubMed] [Google Scholar]
  20. Uhr J. W. Delayed hypersensitivity. Physiol Rev. 1966 Jul;46(3):359–419. doi: 10.1152/physrev.1966.46.3.359. [DOI] [PubMed] [Google Scholar]
  21. WAKSMAN B. H. THE LOCAL REACTION OF CELLULAR HYPERSENSITIVITY. Ann N Y Acad Sci. 1964 Aug 27;116:1045–1051. doi: 10.1111/j.1749-6632.1964.tb52566.x. [DOI] [PubMed] [Google Scholar]
  22. Willms-Kretschmer K., Flax M. H., Cotran R. S. The fine structure of the vascular response in hapten-specific delayed hypersensitivity and contact dermatitis. Lab Invest. 1967 Sep;17(3):334–349. [PubMed] [Google Scholar]

Articles from The American Journal of Pathology are provided here courtesy of American Society for Investigative Pathology

RESOURCES