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. 1993 Aug;175(15):4905–4906. doi: 10.1128/jb.175.15.4905-4906.1993

Delayed expression of in vivo restriction activity following conjugal transfer of Escherichia coli hsdK (restriction-modification) genes.

A Prakash-Cheng 1, J Ryu 1
PMCID: PMC204944  PMID: 8393010

Abstract

Following conjugal transfer of the hsdK genes (hsdRK, hsdMK, and hsdSK) of Escherichia coli K-12, restriction activity was first detected only after approximately 15 generations, whereas modification activity was observed immediately. This sequential expression explains the establishment of hsdK genes in a nonmodified host and suggests regulation of restriction activity after conjugal transfer.

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Selected References

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