Vol. 170 No. 6, September 12, 2005. Pages 903–912.
The editors of The Journal of Cell Biology have been notified by Dr. Gerard C. Grosveld of St. Jude Children's Research Hospital, Memphis, TN, that he and the other authors of the above article wish to retract the paper.
The authors state:
“Figure 1 of this paper was described as reflecting an experiment that showed that the expression of the FOXO1a protein was downregulated in primary tumor samples of alveolar rhabdomyosarcoma patients. In follow-up experiments, however, we have shown that the lack of FOXO1a expression reported in Figure 1 is not correct. We are now certain that primary alveolar rhabdomyosarcoma cells do express FOXO1a protein.
Given that the lack of FOXO1a protein in primary tumors was the basis for proposing that FOXO1a acts as a tumor suppressor in this childhood tumor, we must retract the paper in its entirety.”