Analysis of the genomic structure of the zebrafish caspase-8 (casp8) gene.
(A) Schematic diagram of the casp8 genes. Both zebrafish and mouse casp8 genes are organized into 10 exons. Black and white boxes indicate the coding and non-coding regions, respectively. (B) Comparison of the splice junction sites in zebrafish, chicken and mouse caspase-8. Arrowheads on the amino acid alignment indicate the splice junction sites in the zebrafish, chicken and mouse genes, respectively. Amino acids essential for catalytic activity are indicated by a box.