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. 1969 Dec;50(6):527–532.

The Synthesis of Sulphated Mucopolysaccharide in Mouse Liver Following Carbon Tetrachloride Injury

II. Quantitation and Partial Characterization of Extracted Mucopolysaccharide

J O'd McGee, R S Patrick
PMCID: PMC2072175  PMID: 4243673

Abstract

The incorporation of 35S-sodium sulphate into normal murine hepatic mucopolysaccharide was studied quantitatively and qualitatively. This incorportion is markedly increased by the induction of acute and chronic liver injury with carbon tetrachloride (CCl4). On the basis of chromatographic analysis and specific degradation procedures, it is evident that such injury induces an exaggeration in the synthesis of chondroitin sulphate A and/or C and heparan sulphate. There is no evidence for the presence of dermatan sulphate or keratan sulphate in normal or damaged liver or for passive binding of 35S-sulphate to hepatic tissue.

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530-3Figs. 4-6
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530-1Figs. 2-3
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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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