Abstract
Staphylococcus aureus and Salmonella dublin were injected intraperitoneally into normal white mice and mice previously made tolerant to E. coli 055 B5 endotoxin. One hour after injection, the animals were killed and blood samples taken; the liver and spleen were removed and homogenized. In all cases, the tissues of endotoxin treated animals contained lower numbers of viable bacteria. When the proteins of the injected bacteria were labelled with tritiated leucine, the radioactivity of the liver, spleen and blood indicated that the numbers of bacteria present in these tissues were unaffected by the endotoxin.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Hill A. W., Hibbitt K. G., Shears A. Endotoxin tolerance and the induction of nonspecific resistance to Salmonella dublin and Streptococcus agalactiae infections in mice. Br J Exp Pathol. 1974 Jun;55(3):269–274. [PMC free article] [PubMed] [Google Scholar]
- MacGregor R. R., Sheagren J. N., Wolff S. M. Endotoxin-induced modification of Plasmodium berghei infection in mice. J Immunol. 1969 Jan;102(1):131–139. [PubMed] [Google Scholar]
- Weinstein M. J., Waitz J. A., Came P. E. Induction of resistance to bacterial infections of mice with poly I-poly C. Nature. 1970 Apr 11;226(5241):170–170. doi: 10.1038/226170a0. [DOI] [PubMed] [Google Scholar]