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. 1960 Jun;14(2):376–396. doi: 10.1038/bjc.1960.44

Hypercitricemia in Human Cancer. Factors concerned in Pathogenesis and Treatment

H M Lemon, J H Mueller, J M Looney, W H Chasen, Marcia Kelman
PMCID: PMC2074230  PMID: 13760761

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. AGRELL I. G., LINDELL S. E., WESTLING H. The influence of the adrenal cortex on the citric acid concentration of the guinea pig's blood serum. Acta Physiol Scand. 1955 Oct 27;34(2-3):135–140. doi: 10.1111/j.1748-1716.1955.tb01232.x. [DOI] [PubMed] [Google Scholar]
  2. BEVER A. T., HISAW F. L., VELARDO J. T. Inhibitory action of desoxycorticosterone acetate, cortisone acetate, and testosterone on uterine growth induced by estradiol-17beta. Endocrinology. 1956 Aug;59(2):165–169. doi: 10.1210/endo-59-2-165. [DOI] [PubMed] [Google Scholar]
  3. BUNKER J. P., STETSON J. B., COE R. C., GRILLO H. C., MURPHY A. J. Citric acid intoxication. J Am Med Assoc. 1955 Apr 16;157(16):1361–1367. doi: 10.1001/jama.1955.02950330001001. [DOI] [PubMed] [Google Scholar]
  4. BYRNES W. W., LEMON H. M., REYNOLDS M. D. Copper-resistant serum acid phosphatase. I. Method and values in health and disease. Cancer Res. 1956 Nov;16(10 Pt 1):943–950. [PubMed] [Google Scholar]
  5. CANARY J. J., KYLE L. H. The interrelations of blood calcium and citric acid. J Lab Clin Med. 1957 Apr;49(4):590–596. [PubMed] [Google Scholar]
  6. CARLSSON A., HOLLUNGER G. The effect of vitamin D on the citric acid metabolism. Acta Physiol Scand. 1954 Aug 20;31(4):317–333. doi: 10.1111/j.1748-1716.1954.tb01143.x. [DOI] [PubMed] [Google Scholar]
  7. CHANG T. S., FREEMAN S. Citric acid and its relation to serum and urinary calcium. Am J Physiol. 1950 Feb;160(2):330–340. doi: 10.1152/ajplegacy.1950.160.2.330. [DOI] [PubMed] [Google Scholar]
  8. COOKSON B. A., COSTAS-DURIEUX J., BAILEY C. P. The toxic effects of citrated blood and the search for a suitable substitute for use in cardiac surgery. Ann Surg. 1954 Apr;139(4):430–438. doi: 10.1097/00000658-195404000-00006. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. DIXON T. F., PERKINS H. R. Citric acid and bone metabolism. Biochem J. 1952 Oct;52(2):260–265. doi: 10.1042/bj0520260. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. ELLIOTT J. R., FREEMAN S. Relative effect of vitamin D and parathyroid extract on plasma calcium and citric acid of normal and thyroparathyroidectomized dogs. Endocrinology. 1956 Aug;59(2):196–200. doi: 10.1210/endo-59-2-196. [DOI] [PubMed] [Google Scholar]
  11. FISHER E. R., TURNBULL R. B., Jr The cytologic demonstration and significance of tumor cells in the mesenteric venous blood in patients with colorectal carcinoma. Surg Gynecol Obstet. 1955 Jan;100(1):102–108. [PubMed] [Google Scholar]
  12. HALLMAN N., FORSANDER O. Citric acid metabolism in acute anoxia in dogs. Ann Med Exp Biol Fenn. 1952;30(3-4):287–292. [PubMed] [Google Scholar]
  13. HENNES A. R., SHREEVE W. W. Hormonal effects on C-14 acetate metabolism in the human. Proc Soc Exp Biol Med. 1959 Feb;100(2):246–250. doi: 10.3181/00379727-100-24587. [DOI] [PubMed] [Google Scholar]
  14. HILL B. R., LEVI C. Elevation of a serum component in neoplastic disease. Cancer Res. 1954 Aug;14(7):513–515. [PubMed] [Google Scholar]
  15. HOWLAND W. S., BELLVILLE J. W., ZUCKER M. B., BOYAN P., CLIFFTON E. E. Massive blood replacement. V. Failure to observe citrate intoxication. Surg Gynecol Obstet. 1957 Nov;105(5):529–540. [PubMed] [Google Scholar]
  16. HUGGINS C., JENSEN E. V. The depression of growth of the uterus, adrenals, and ovaries by fluorinated steroids in the pregnane series. J Exp Med. 1955 Sep 1;102(3):347–360. doi: 10.1084/jem.102.3.347. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. KISSIN B., KREEGER N. Serum citric acid in Paget's disease. Am J Med Sci. 1954 Sep;228(3):301–305. [PubMed] [Google Scholar]
  18. MARKS P. A., BISHOP J. S. The glucose metabolism of patients with malignant disease and of normal subjects as studied by means of an intravenous glucose tolerance test. J Clin Invest. 1957 Feb;36(2):254–264. doi: 10.1172/JCI103419. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. MILLER H., CARRUTHERS C. Citric acid metabolism in carcinogenesis and its relationships to calcium metabolism. Cancer Res. 1950 Oct;10(10):636–641. [PubMed] [Google Scholar]
  20. MOORE G. E., SANDBERG A., SCHUBARG J. R. Clinical and experimental observations of the occurrence and fate of tumor cells in the blood stream. Ann Surg. 1957 Oct;146(4):580–587. doi: 10.1097/00000658-195710000-00005. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. PEARSON O. H., LI M. C., MACLEAN J. P., LIPSETT M. B., WEST C. D. The use of hydrocortisone in cancer. Ann N Y Acad Sci. 1955 May 27;61(2):393–396. doi: 10.1111/j.1749-6632.1955.tb42489.x. [DOI] [PubMed] [Google Scholar]
  22. POTTER V. R., BUSCH H. Citric acid content of normal and tumor tissues in vivo following injection of fluoroacetate. Cancer Res. 1950 Jun;10(6):353–356. [PubMed] [Google Scholar]
  23. Pincus J. B., Natelson S., Lugovoy J. K. IV. RESPONSE OF CITRIC ACID LEVELS OF NORMAL ADULTS AND CHILDREN TO INTRAMUSCULAR INJECTION OF EPINEPHRINE. J Clin Invest. 1949 Jul;28(4):741–745. doi: 10.1172/JCI102126. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. ROTTINO A., HOFFMANN G. T., BRONDOLO B. Serum citric acid in Hodgkin's disease, lymphoma and carcinoma. Proc Soc Exp Biol Med. 1952 Jun;80(2):339–341. doi: 10.3181/00379727-80-19616. [DOI] [PubMed] [Google Scholar]
  25. SIBLEY J. A., FLEISHER G. A., HIGGINS G. M. Significance of the level of serum aldolase in tumor-bearing animals. Cancer Res. 1955 Jun;15(5):306–314. [PubMed] [Google Scholar]
  26. WOLFSON S. K., SPENCER J. A., STERKEI R. L., WILLIAMS-ASHMAN H. G. Clinical and experimental studies on serum pyridine nucleotide-linked dehydrogenases in liver damage. Ann N Y Acad Sci. 1958 Oct 13;75(1):260–269. doi: 10.1111/j.1749-6632.1958.tb36872.x. [DOI] [PubMed] [Google Scholar]
  27. Wexler I. B., Pincus J. B., Natelson S., Lugovoy J. K. III. THE FATE OF CITRATE IN ERYTHROBLASTOTIC INFANTS TREATED WITH EXCHANGE TRANSFUSION. J Clin Invest. 1949 May;28(3):474–481. doi: 10.1172/JCI102093. [DOI] [PMC free article] [PubMed] [Google Scholar]

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