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British Journal of Cancer logoLink to British Journal of Cancer
. 1996 Jan;73(2):241–245. doi: 10.1038/bjc.1996.42

Application of the multidimensional fatigue inventory (MFI-20) in cancer patients receiving radiotherapy.

E M Smets 1, B Garssen 1, A Cull 1, J C de Haes 1
PMCID: PMC2074317  PMID: 8546913

Abstract

In this paper the psychometric properties of the multidimensional fatigue inventory (MFI-20) are established further in cancer patients. The MFI is a 20-item self-report instrument designed to measure fatigue. It covers the following dimensions: general fatigue, physical fatigue, reduced activity, reduced motivation and mental fatigue. The instrument was used in a Dutch and Scottish sample of cancer patients receiving radiotherapy. The dimensional structure was assessed using confirmatory factor analyses (Lisrel's unweighted least-squares method). The hypothesised five-factor model appeared to fit the data in both samples (adjusted goodness of fit; AGFI: 0.97 and 0.98). Internal consistency of the separate scales was good in both the Dutch and Scottish samples with Cronbach's alpha coefficients ranging from 0.79 to 0.93. Construct validity was assessed by correlating the MFI-20 to activities of daily living, anxiety and depression. Significant relations were assumed. Convergent validity was investigated by correlating the MFI scales with a visual analogue scale measuring fatigue and with a fatigue-scale derived from the Rotterdam Symptom Checklist. Results support the validity of the MFI-20. The highly similar results in the Dutch and Scottish sample suggest that the portrayal of fatigue using the MFI-20 is quite robust.

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Selected References

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  1. Berglund G., Bolund C., Fornander T., Rutqvist L. E., Sjödén P. O. Late effects of adjuvant chemotherapy and postoperative radiotherapy on quality of life among breast cancer patients. Eur J Cancer. 1991;27(9):1075–1081. doi: 10.1016/0277-5379(91)90295-o. [DOI] [PubMed] [Google Scholar]
  2. Blesch K. S., Paice J. A., Wickham R., Harte N., Schnoor D. K., Purl S., Rehwalt M., Kopp P. L., Manson S., Coveny S. B. Correlates of fatigue in people with breast or lung cancer. Oncol Nurs Forum. 1991 Jan-Feb;18(1):81–87. [PubMed] [Google Scholar]
  3. Devlen J., Maguire P., Phillips P., Crowther D., Chambers H. Psychological problems associated with diagnosis and treatment of lymphomas. I: Retrospective study. Br Med J (Clin Res Ed) 1987 Oct 17;295(6604):953–954. doi: 10.1136/bmj.295.6604.953. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Fobair P., Hoppe R. T., Bloom J., Cox R., Varghese A., Spiegel D. Psychosocial problems among survivors of Hodgkin's disease. J Clin Oncol. 1986 May;4(5):805–814. doi: 10.1200/JCO.1986.4.5.805. [DOI] [PubMed] [Google Scholar]
  5. Hayes J. R. Depression and chronic fatigue in cancer patients. Prim Care. 1991 Jun;18(2):327–339. [PubMed] [Google Scholar]
  6. Nerenz D. R., Leventhal H., Love R. R. Factors contributing to emotional distress during cancer chemotherapy. Cancer. 1982 Sep 1;50(5):1020–1027. doi: 10.1002/1097-0142(19820901)50:5<1020::aid-cncr2820500534>3.0.co;2-j. [DOI] [PubMed] [Google Scholar]
  7. Rhodes V. A., Watson P. M., Hanson B. M. Patients' descriptions of the influence of tiredness and weakness on self-care abilities. Cancer Nurs. 1988 Jun;11(3):186–194. [PubMed] [Google Scholar]
  8. Smets E. M., Garssen B., Bonke B., De Haes J. C. The Multidimensional Fatigue Inventory (MFI) psychometric qualities of an instrument to assess fatigue. J Psychosom Res. 1995 Apr;39(3):315–325. doi: 10.1016/0022-3999(94)00125-o. [DOI] [PubMed] [Google Scholar]
  9. Smets E. M., Garssen B., Schuster-Uitterhoeve A. L., de Haes J. C. Fatigue in cancer patients. Br J Cancer. 1993 Aug;68(2):220–224. doi: 10.1038/bjc.1993.319. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Zigmond A. S., Snaith R. P. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983 Jun;67(6):361–370. doi: 10.1111/j.1600-0447.1983.tb09716.x. [DOI] [PubMed] [Google Scholar]
  11. de Haes J. C., van Knippenberg F. C., Neijt J. P. Measuring psychological and physical distress in cancer patients: structure and application of the Rotterdam Symptom Checklist. Br J Cancer. 1990 Dec;62(6):1034–1038. doi: 10.1038/bjc.1990.434. [DOI] [PMC free article] [PubMed] [Google Scholar]

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