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. 1996 Feb;73(4):553–556. doi: 10.1038/bjc.1996.96

Human papillomavirus infection and risk of progression of epithelial abnormalities of the cervix.

C B Woodman 1, T Rollason 1, J Ellis 1, R Tierney 1, S Wilson 1, L Young 1
PMCID: PMC2074466  PMID: 8595174

Abstract

The polymerase chain reaction has been used to determine the presence of human papillomavirus (HPV) 16 and HPV 18 DNA sequences in archival histological material removed from a cohort of untreated women with cervical epithelial abnormalities. The detection of HPV 16 or HPV 18 DNA sequences in the initial biopsy specimen was associated with a significantly increased risk of subsequent disease progression.

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Selected References

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