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. 1992 Dec;174(24):7963–7970. doi: 10.1128/jb.174.24.7963-7970.1992

Structures of the O1B and O1C lipopolysaccharide antigens of Escherichia coli.

D S Gupta 1, A S Shashkov 1, B Jann 1, K Jann 1
PMCID: PMC207532  PMID: 1281148

Abstract

The O-specific moieties of the O1B antigen (lipopolysaccharide) from Escherichia coli O1B:K1 and the O1C antigen from E. coli O1C:K- both consist of L-rhamnose, D-galactose, N-acetyl-D-glucosamine, and N-acetyl-D-mannosamine in a molar ratio of 2:1:1:1. By using fragmentation procedures, methylation analysis, and one- and two-dimensional nuclear magnetic resonance spectroscopy, the structures of these polysaccharides were found to be [formula: see text] In the O1B polysaccharide X is 2, and in the O1C polysaccharide X is 3. With the recently published structure of the O1A polysaccharides (B. Jann, A. S. Shashkov, D. S. Gupta, S. M. Panasenko, and K. Jann, Carbohydr. Polym. 18:51-57 1992), three related O1 antigens are now known. Their common (O1-specific) epitope is suggested to be the side-chain N-acetyl-D-mannosamine residue.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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