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. 1992 Oct;174(19):6314–6316. doi: 10.1128/jb.174.19.6314-6316.1992

Inhibition of cell division initiation by an imbalance in the ratio of FtsA to FtsZ.

S J Dewar 1, K J Begg 1, W D Donachie 1
PMCID: PMC207705  PMID: 1400183

Abstract

Elevated levels of FtsA protein block cell division at a very early stage, similar to that caused by inhibition of the action of FtsZ. In contrast, overexpression of FtsA and FtsZ together does not block division. A specific ratio of FtsA to FtsZ protein, therefore, is required for cell division.

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Selected References

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